Protein Alignment CG33287 and Dnai7

DIOPT Version :10

• Sequence 1: NP_001137993.1
• Gene: CG33287 / 2768986
• FlyBaseID: FBgn0053287
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: XP_038963394.1
• Gene: Dnai7 / 297720
• RGDID: 1311213
• Length: 767
• Species: Rattus norvegicus
• Alignment Length: 1113
• Identity: 183/1113 - (16%)
• Similarity: 316/1113 - (28%)
• Gaps: 515/1113 - (46%)

  Fly    44 SLLQFRLLEEERTNQ-----GRWDQYLRCDGLPKVRSPIEIRTFLAKIRHFEEIETKNSIDWTMG 103
            :||:....|.|:..:     .:|..|..|||.|..|...|:.||::.   :||
  Rat   115 ALLECCFPEAEKQKREMRVLAQWKHYTECDGSPDPRIAQEMNTFISL---WEE------------ 164

  Fly   104 VDERSVLSQNIYQKDLTRPVLQRTAVDNPGSYFESNLKKCMDVLQQVDILMDNEVEMERMNKSVL 168
                                             |.|     :..:||            |.||.|
  Rat   165 ---------------------------------EKN-----ETFEQV------------MEKSKL 179

  Fly   169 V-DLLEVYRDVQLEIESL-FDR---LTYR--ILRMQKAYMESVNG----IVARWSHSCDLWRMDL 222
            | .|:|..:.:.||..|. .|:   |.|:  |||:|:.....||.    ::.:.|:..||
  Rat   180 VLSLIEKLKLILLETPSCDLDKSTVLQYQGSILRLQELLSLKVNVATELLLRQASNLADL----- 239

  Fly   223 WGLYNVPIIFQQLEVPLMI------------VDFKETSVKVQVPLSVLCDCITIRCVHTDFDHHS 275
             ...|:..|.:...|.|.:            |.|.:|.|..::|..:....:.:|.:||.:||.:
  Rat   240 -DTGNMEKIIKDENVTLYVWANLKKNPRYRTVKFSQTQVGFEIPRILATSNVALRLLHTHYDHIT 303

  Fly   276 PHAKSYEPLTVESIFMPNAGLTDMEESVVGEWLMQNDIQEETLNNMNRRREEYDELMQLIAERTE 340
            |   .:..:..|          :...|:|.|     :.:||                    ||||
  Rat   304 P---LFSTVVTE----------EKHGSIVAE-----NFKEE--------------------ERTE 330

  Fly   341 QAAKEAKFGKGGDGDKRPKIVIPKTPKTVPLVPQGMYPDVFKEFLFREEDQYKKFLSTYFHPDNL 405
            :|..|                                .:||.|....|.:|.|.     .....|
  Rat   331 KAVPE--------------------------------ENVFTEEAADEAEQLKA-----EEEREL 358

  Fly   406 SLTPEEVNLRECIIVGGIYNISFVRRPDQTQFEKFNIVLHEDGRVLKVIPQVVAKQDNRKSRLTE 470
            |..|||                      :.:|:.          .:..:.|.::..:..:|:.|:
  Rat   359 SSIPEE----------------------EVKFDP----------TVDTVTQKISDPEEEESQTTQ 391

  Fly   471 Y------TRMTLGTSQMKLSEE--ELPFFVVTVQLPPHLCRWGKPEVCHYLRELQTPTRAPDRST 527
            :      ...|:..:|:.|.|.  |:|     ..|.|:     :..:||:
  Rat   392 FELERKLLSETVSAAQLSLIENVLEMP-----ETLEPY-----EVNMCHF--------------- 431

  Fly   528 LVTLNVLSPIRISSELSKREDGSVQSTLANQFSPPLKSLLKQSITYGHFPLRGEPIANFNLDKSL 592
                   :|:           |.|......:..|..|            |::|..:|... .:.|
  Rat   432 -------APL-----------GGVYHLEILELPPQSK------------PVKGWVLAEIR-QEGL 465

  Fly   593 NKIEIMKLEKMCLPRIISSFKFPSEFVEDQLTSEALKSRPNRLVKRLDTETAVEAKTPAEIYFEY 657
            .|                 |.:|.|..|:          |:
  Rat   466 QK-----------------FTYPPENTEE----------PD------------------------ 479

  Fly   658 ESQERPERAFPIFEKTVAIEFSSAAELMPSIECGNKATACGLLSTLEDIKEKYLQRPQELLDQIQ 722
                 ||.|||..|.|:.|..|:.                            :.:.||.:
  Rat   480 -----PESAFPPIEVTLEIHESAI----------------------------FFEDPQVV----- 506

  Fly   723 VQVSKKSEKKAEKWENKNADGRSSAFSFRDRSSFANVNGKKTALDAKTKINETEIMITISTSENK 787
                        :|:   |:|:
  Rat   507 ------------RWD---AEGK------------------------------------------- 513

  Fly   788 MEIPSTSKTRTRRSGSVMKRRSTRKSARMEDMDRFRPMDSEPPVLLDHWTKEYIMESQINLETNT 852
                                                           .|..:.:.....|.|...
  Rat   514 -----------------------------------------------FWRSDGVTCVYYNRENRL 531

  Fly   853 LTFRTDRLGIFGLAFKRYEHFPFRDWCLQPSEDNPDEVILSLDTFHVRMFFYI-------SARGV 910
            |||..|.:|...|....:.:.|::.|.|.|...|  :.:|.:.|..:.:..:|       :|..:
  Rat   532 LTFSIDTMGPVTLIQDAHVNMPYQSWELSPLGMN--KALLMVTTVFIELQIHIKETHCMLAAVKL 594

  Fly   911 RGYVTDL-VKGYTAKPVKYLEIVEPISDFRELRKLLIERNLNIFAENDASYYITNGYFSIKHIAL 974
            :|...:| |.|....|:.::             ..|.|..||||....:.:|:.   .:.|...:
  Rat   595 KGKSRELRVIGKWMTPIPFI-------------LALKEAGLNIFPAVYSHFYVV---VNNKVPQM 643

  Fly   975 ELHTYNTMALQCKLMKFCRSSWNRLAQRRDIIVEMK--IAKDNSDYSEVTMRITPEKTTFVKISE 1037
            ||..|..|||......|..|.||.:.....::..::  |:::....:...:..:.::...:|:.|
  Rat   644 ELKAYRQMALLSSAFSFGWSKWNMVCNSTRVVFRVREHISEEEEQNTWALLMFSGDRAQMLKMQE 708

  Fly  1038 MCSDDVNVVKLRYEDTWRNVNNYNDFGQAIYSL-----NPHTLEGSNKDAMLFV----YLKRLLN 1093
            . ||       ::.:|.|   ..::|...:|.:     :|...|........|:    |   :|.
  Rat   709 E-SD-------QFSETLR---EGSEFHSTLYHMMKDFASPEATEKVRHSNCQFIDSVCY---MLL 759

  Fly  1094 EIRPLSYS 1101
            .:|.||||
  Rat   760 SVRVLSYS 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33287	NP_001137993.1	Casc1_C	835..1053	CDD:432508	46/227 (20%)
Dnai7	XP_038963394.1	Casc1_N	37..266	CDD:464947	46/221 (21%)