Protein Alignment CG33287 and CG33286

DIOPT Version :10

• Sequence 1: NP_001137993.1
• Gene: CG33287 / 2768986
• FlyBaseID: FBgn0053287
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: NP_001097653.1
• Gene: CG33286 / 2768984
• FlyBaseID: FBgn0053286
• Length: 1062
• Species: Drosophila melanogaster
• Alignment Length: 1129
• Identity: 552/1129 - (48%)
• Similarity: 742/1129 - (65%)
• Gaps: 95/1129 - (8%)

  Fly     1 MGKEGGTTTETPV--------LISEAEMMERQKNYTTRMHDIAAACATFRKSLLQFRLLEEERTN 57
            |.|...|....||        ||||.|:|:|:..|.:|::|...:....:.:...|...|.:|..
  Fly     1 MVKRKSTAAAKPVAEPILRYPLISENEVMDREARYMSRLNDFTVSAELVKGAQRDFYNQEVDRMF 65

  Fly    58 QGRWDQYLRCDGLPKVRSPIEIRTFLAKIRHFEEIETKNSIDWTMGVDERSVLSQNIYQKDLTRP 122
            :..|:.:|||||||:...|:|:|||::|||.::||||.||:|||:.|||||:|:|||::.|.||.
  Fly    66 REHWEHHLRCDGLPRPYLPVEVRTFMSKIRFYDEIETNNSMDWTLSVDERSILTQNIFRVDKTRR 130

  Fly   123 VLQRTAVDNPGSYFESNLKKCMDVLQQVDILMDNEVEMERMNKSVLVDLLEVYRDVQLEIESLFD 187
            ::. ...||||.:::.|::.|::.|:|:|.::|||.||.||:.....|::|||.:|:.||..|||
  Fly   131 MMM-VNKDNPGEHYDHNVQMCLNALKQMDAMLDNEAEMVRMSDKRQKDVIEVYTEVEAEIGDLFD 194

  Fly   188 RLTYRILRMQKAYMESVNGIVARWSHSCDLWRMDLWGLYNVPIIFQQLEVPLMIVDFKETSVKVQ 252
            |||||:|.||.|||||.:|.||.||::|:.||:|||||.||||||.|||:|:|:.:|..|||:||
  Fly   195 RLTYRVLSMQDAYMESKDGRVAVWSYTCNPWRLDLWGLRNVPIIFDQLELPVMLAEFSATSVEVQ 259

  Fly   253 VPLSVLCDCITIRCVHTDFDHHSPHAKSYEPLTVESIFMPNAGLTDMEESVVGEWLMQNDIQEET 317
            :|.|||.||:|||.:|.|||:.|.:|||:|.....|:..||||:.|:|.|||.||.||.:|||||
  Fly   260 IPKSVLKDCVTIRSLHMDFDNISQNAKSFEIAVKASLNYPNAGIVDIENSVVNEWHMQLEIQEET 324

  Fly   318 LNNMNRRREEYDELMQLIAERTEQAAKEAKFGKGGDGDKRPKIVIPKTPKTVPLVPQGMYPDVFK 382
            ||.|..||.||:::|:||||:||||||.|   |..|.||..||.|||.||..|.||.||:||:::
  Fly   325 LNLMLTRRREYEDMMELIAEKTEQAAKAA---KQTDPDKMVKITIPKAPKEPPYVPTGMFPDIYE 386

  Fly   383 EFLFREEDQYKKFLSTYFHPDNLSLTPEEVNLRECIIVGGIYNISFVRRPDQTQFEKFNIVLHED 447
            :||..||.||..:|....||.:|.:.|.|:|||:.|::||||:|.|:|||||||||:||||||||
  Fly   387 DFLRIEESQYSGYLDEVCHPRHLDMQPFEINLRDYIMLGGIYSIMFIRRPDQTQFEQFNIVLHED 451

  Fly   448 GRVLKVIPQVVAK---QDNRKSRLTEYTRMTLGTSQMKLSEEELPFFVVTVQLPPHLCRWGKPEV 509
            |||:.::.::.|.   :..|||.:...||.|...:::||.::|||:|:||:|:...||:|.:|.|
  Fly   452 GRVVHILTEMKADIPVEAVRKSNIGRKTRETYRGTKIKLEDDELPYFIVTLQVAADLCKWSEPVV 516

  Fly   510 CHYLRELQ-TPTRAPDRSTLVTLNVLSPIRISSELSKRE----DGSVQSTLANQFSPPLKSLLKQ 569
            ||::.|.. .||.....|..|. .:.|.|| .||.:.|.    ...:....||.|.|.|:|.|:|
  Fly   517 CHFITEKDFIPTDYKRESYWVP-TMQSVIR-HSEYAGRSMLNLGSQISGDSANIFRPSLRSFLRQ 579

  Fly   570 SITYGHFPLRGEPIANFNLDKSLNKIEIMKLEKMCLPRIISSFKFPSEFVEDQLTSEALKSRPNR 634
            | ..|..|..|.||.:|.|:|.|:.:||..|||.||||||||||||.:|.:::  .|.::..|..
  Fly   580 S-KVGAAPKPGVPIEDFKLEKKLSHLEIRTLEKYCLPRIISSFKFPVDFRDEK--REFIRQGPRA 641

  Fly   635 LVKRLDTETAV-EAKTPAEIYFEYESQE-RPERAFPIFEKTVAIEFSSAAELMPSIECG--NKAT 695
            ||||.|.|..| :.||   :.|.|.||. .|||.:|.|.:...|::....:   .:|.|  |..:
  Fly   642 LVKRPDAEEVVTQVKT---LDFNYNSQVLGPERMYPYFPQMDPIKYPIPFD---DLEPGPVNPTS 700

  Fly   696 ACGLLSTLEDIKEKYLQRPQELLDQIQVQVSKKSEKKAEKWENKNADGRSSAFSFRDRSSFANVN 760
            |..||.|.::||.||.::..:|:.|...| .|||::
  Fly   701 ALELLKTFDNIKSKYQEKHIDLISQPDEQ-DKKSKQ----------------------------- 735

  Fly   761 GKKTALDAKTKINETEIMITISTSENKMEIPSTSKTRTRRSGSVMKRRSTRKSARMEDMD----- 820
             ||..:..:..:.|.:|                :|.:..:.|.  |.||:.|:.||:.:.
  Fly   736 -KKLGVKEEDDVPEAQI----------------AKRKFSKLGD--KVRSSVKTDRMDRVTVGSDK 781

  Fly   821 ---RFRPMDSEPPVLLDHWTKEYIMESQINLETNTLTFRTDRLGIFGLAFKRYEHFPFRDWCLQP 882
               :..||..|.   :.|||.:|:.:..|:.|||::||:|||||:.|||||||||||||:|.|||
  Fly   782 SSVKTNPMSEEQ---VTHWTTKYVKDVVIDRETNSITFKTDRLGLLGLAFKRYEHFPFRNWSLQP 843

  Fly   883 SEDNPDEVILSLDTFHVRMFFYISARGVRGYVTDLVKGYTAKPVKYLEIVEPISDFRELRKLLIE 947
            :|:||||:||.:||||||:||||:.:|||||||||.|||||||:|||||||||||||::|::.|.
  Fly   844 NEENPDEIILCVDTFHVRIFFYITCKGVRGYVTDLSKGYTAKPIKYLEIVEPISDFRQMRQIFIS 908

  Fly   948 RNLNIFAENDASYYITNGYFSIKHIALELHTYNTMALQCKLMKFCRSSWNRLAQRRDIIVEMKIA 1012
            :|:|||||||||:||.|||||:||:|||:||||.|||.||||||.||||||||.|||||:.||||
  Fly   909 KNINIFAENDASFYIENGYFSMKHVALEMHTYNIMALHCKLMKFYRSSWNRLADRRDIIMGMKIA 973

  Fly  1013 KDNSDYSEVTMRITPEKTTFVKISEMCSDDVNVVKLRYEDTWRNVNNYNDFGQAIYSLNPHTLEG 1077
            |||||||||||||||||||||:|||.|||.|||:.|.|.:||||:.|:.|..|||.|:.|:..|.
  Fly   974 KDNSDYSEVTMRITPEKTTFVQISENCSDKVNVIVLNYINTWRNIGNFTDLHQAINSMVPNATEV 1038

  Fly  1078 SNKDAMLFVYLKRLLNEIRPLSYS 1101
            .|||::|..|:.|:|.|||.||:|
  Fly  1039 RNKDSILLYYVTRMLKEIRLLSFS 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33287	NP_001137993.1	Casc1_C	835..1053	CDD:432508	164/217 (76%)
CG33286	NP_001097653.1	Casc1_C	793..1014	CDD:432508	164/223 (74%)