Protein Alignment CG33287 and LOC1269736

DIOPT Version :10

• Sequence 1: NP_001137993.1
• Gene: CG33287 / 2768986
• FlyBaseID: FBgn0053287
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: XP_061498854.1
• Gene: LOC1269736 / 1269736
• VectorBaseID: AGAMI1_006499
• Length: 1039
• Species: Anopheles gambiae
• Alignment Length: 1191
• Identity: 256/1191 - (21%)
• Similarity: 454/1191 - (38%)
• Gaps: 310/1191 - (26%)

  Fly    13 VLISEAEMMERQKNYTTRMHDIAAACATFRKSLLQFRLLEEERTNQGRWDQYLRCDGLPKVRSPI 77
            ::.::...::.:::||.    :|:.....||.|..   .::||    .|:||:||:|||....|.
Mosquito    57 IVANKLRKVQLEESYTY----LASIREEVRKVLAD---AKKER----EWEQYMRCNGLPNAFDPA 110

  Fly    78 EIRTFL----AKIRHFEEIETKNSIDWTMGVDERSVLSQNIYQKDLTRPVLQRTAVDNP--GSYF 136
            ::|.:|    ..||...|.|.    :|.:..:|:|:|:||:...:|:   ::...:..|  |:.:
Mosquito   111 DLRKYLHIWCENIRDTNEAER----NWLLQTNEQSILTQNVNVANLS---MESLKLQQPQIGNTY 168

  Fly   137 ESNLKKCMDVLQQVD-ILMDNEVEMERMNKSVLVDLLEVYRDVQLEIESLFDRLTYRILRMQKAY 200
            .:...:.:.:|:::| .|.|::|     ..|::.||.|:..:.:..:....|...|:||......
Mosquito   169 AAKAVEVLGILEEIDEALHDSDV-----RPSMVEDLNELKMEFRNVLADYIDEFAYKILSNINRD 228

  Fly   201 MESVNGIVARWSHSCD--LWRMDLWGLYNVPIIFQQL--------EVPLMIVDFKETSVKVQVPL 255
            || :||:: ..||..:  :::..|:||.::|.  .||        :.....:||......:.:|.
Mosquito   229 ME-LNGLL-EVSHKFESPVFKTHLFGLRDMPT--PQLNPKERAKEDSKHTSIDFPSLGFHLTLPA 289

  Fly   256 SVLCDCITIRCVHTDFDHHSPHAKSYEPLTVESIFMP--NAGLTDMEESVVGEWLMQNDIQEETL 318
            :|.|....||.:...:||.|.:..||:        ||  ...|.|:......||..:.:|.:...
Mosquito   290 AVKCHKAAIRGLWISYDHCSDYCPSYD--------MPYKQENLADLRIISRIEWKKRKEILKAVY 346

  Fly   319 NNMNRRREEYDELMQLIAERTEQAAKEAKFGKGGDGDKRPKIVIPKTPKTVPLVPQGMYPDVFKE 383
            .....::.:.||        .:|..::.      |.||                   :|.:...|
Mosquito   347 EEPKEKKTDSDE--------DDQTPQDI------DVDK-------------------IYTEHADE 378

  Fly   384 FLFREEDQYKKFLSTYFHPDNLSLTPEEVNLRECIIVGGIYNISFVRRPDQTQFEKFNIVLHEDG 448
            .:  ::::.||...|      |:|:..:||:|...||.|:|.|.::.:|.|.       |.....
Mosquito   379 LM--KKERTKKGAKT------LNLSEYDVNMRSHRIVAGVYAIDYLEQPMQD-------VKIAKK 428

  Fly   449 RVLKVIPQVVAKQDNRK---------------SRLTEYTRMTLGTSQMKLSEEEL-PFFVVTVQL 497
            .:|:.:|| ..|...:|               .||.|...     :::|..||.| ...:|:|.|
Mosquito   429 TLLRTVPQ-PGKLKRKKFYQPYRPPPTPQPGVRRLPEEIE-----AEIKQMEENLDKLALVSVLL 487

  Fly   498 --------PPHLCRW--------GKPEVCHYLRELQTPTRAPDRSTLVTLNVLSPIRISSELSKR 546
                    ||.:|||        ..|....||..|:...:|                 :.|.::|
Mosquito   488 PENVFWFEPPIVCRWELKEETLESDPNFAKYLDRLEKAQQA-----------------ARERNER 535

  Fly   547 EDGSVQSTLANQFS----PPLKSLLKQSITYGHFPLRGEPIANFNLDKSLNKIEIMKLEKMCLPR 607
            .:...::.....|:    |.            |.|||. .:.:|                 .:|:
Mosquito   536 SNLDRRTKYVEDFNILDVPQ------------HIPLRA-IVTDF-----------------VIPK 570

  Fly   608 IISSFKFPSEFVED-----QLTSEA------LKSRPNRLVKRLDTETAV-----EAKTPAEIYFE 656
            :..|........||     |.|:.|      ..|:..|.:.::.:..::     |.|.|..:|
Mosquito   571 LPDSCSIKISVAEDKRRAAQPTAVAGSGGGKRSSKQKRRLHKMPSNVSLGSIVYETKIPDFLY-- 633

  Fly   657 YESQERPERAFPIFEKTVAIEFSSAAELMPSIEC----GNKATACGLLSTLEDIKEKYLQRPQEL 717
              :...|.|...:.::.             :.:|    |...:     ..|:|..|.
Mosquito   634 --ATRNPLRILKVLDRR-------------NRQCYPYAGTSDS-----DDLDDYDES-------- 670

  Fly   718 LDQIQVQVSKKSEKKAEKWENKNADGRSSAFSFRDRSSFAN-----VNGKKTALDAKTKINETEI 777
             |...||               |...:...:.|   |||..     :..|...|.||.   |.|:
Mosquito   671 -DNDVVQ---------------NRSTKRKVYMF---SSFMKDLDELLESKSPKLQAKL---EQEL 713

  Fly   778 MI---TISTSENKMEIPSTSKTRTRRSGSVMKRRSTRKS---ARMEDMD--------RFRPMDSE 828
            ..   |....:..:::..:.:|||.|.....|.:...||   :..||:|        .:..::::
Mosquito   714 GAGGPTGGPGKQSLQVARSDETRTVRGEKGEKGKKPAKSKFDSDDEDVDYGNILEVGNYSMVEND 778

  Fly   829 PPVLLDHWTKEYIMESQINLETNTLTFRTDRLGIFGLAFKRYEHFPFRDWCLQPSEDNPDEVILS 893
            .. .:..|:...:.:.:.|.:..|:.||..|||.|..|..||.:.|::.|.|:|...||..|..|
Mosquito   779 KR-YIGKWSTRDVHDVKFNEDKLTIQFRVGRLGSFAFAANRYSNVPYQSWELKPDIKNPGTVTFS 842

  Fly   894 LDTFHVRMFFYISARGVRGYVTDLVKGYTAKPVKYL-EIVEPISDFRELRKLLIERNLNIFAEND 957
            |....|.....|:..|.|  |..|..|    |.:.| ||:......|:|.|.|....:::|.|:|
Mosquito   843 LTASVVSTEMTITEAGFR--VNSLQGG----PTQALQEILGLTMSLRKLIKTLRLAAVDLFPEDD 901

  Fly   958 ASYYITNGYFSIKHIALELHTYNTMALQCKLMKFCRSSWNRLAQRRDIIVEMK-IAKDNSDYSEV 1021
            |..| |.|... |:..:|.|.|:.:.|......|..|.||.|:..|..::.|: |.:.....:..
Mosquito   902 AFNY-TEGTCE-KNPIMESHLYDCIGLLALTHNFSWSRWNLLSGCRMCVLLMREIVEHRRLPNHS 964

  Fly  1022 TMRITPEKTTFVKISEMCSDDVNVVKLRYEDTWRNVNNYNDFGQAIYSLNPHTLEGSNK------ 1080
            |:.:||.|.:.:       |.|.|..:...:....:|:|.|    :|.|.....:.|::
Mosquito   965 TLLVTPLKASVI-------DTVEVSPVFNPNPVEGMNHYAD----LYHLGRDQSQPSSRIKQEKM 1018

  Fly  1081 DAMLFVYLKRLLNEIRPLSYS 1101
            ..:|...:.:||..:||||:|
Mosquito  1019 SPILRENVTQLLKSVRPLSFS 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33287	NP_001137993.1	Casc1_C	835..1053	CDD:432508	63/219 (29%)
LOC1269736	XP_061498854.1	None