Protein Alignment CG33287 and LOC11175834

DIOPT Version :10

• Sequence 1: NP_001137993.1
• Gene: CG33287 / 2768986
• FlyBaseID: FBgn0053287
• Length: 1101
• Species: Drosophila melanogaster
• Sequence 2: XP_061503625.1
• Gene: LOC11175834 / 11175834
• VectorBaseID: AGAMI1_002480
• Length: 1180
• Species: Anopheles gambiae
• Alignment Length: 1208
• Identity: 282/1208 - (23%)
• Similarity: 489/1208 - (40%)
• Gaps: 233/1208 - (19%)

  Fly    25 KNYTTRMHDIAAACATFRKSLLQFRLLEEERTNQGR--WDQYLRCDGLPKVRSPIEIRTFLAKIR 87
            |.|..|...:......||:  |:...|:.||....|  |..:|.|...|...||..:|..|.:.|
Mosquito    75 KEYNQRRMLLVETVKFFRR--LEKAALDHERQQAERKEWTDFLACRTAPDPASPPLLREALYRWR 137

  Fly    88 HFEEIETKNSIDWTMGVDERSVLSQNIYQKDLTRPVLQRTAVDNPGSYFESNLKKCMDVLQQV-D 151
            ..:|...|:|:.||:..||||.|:|:..:|..||..| |....|.|..:...:::.:.||..: |
Mosquito   138 FQQEALEKSSVSWTLAADERSPLTQDPSRKRTTRKDL-REVFRNIGGLYLPTVREALAVLASIQD 201

  Fly   152 ILMDNEVEMERMNKSVLVDLLEVYRDVQLEIESLFDRLTYRILRMQKAYMESVNGIVARWS-HSC 215
            .:.......|.|...|.:...|:.:.:.   :|| ||:|:||.......||:::.:::.:. ...
Mosquito   202 SVQGKGPRHETMPAEVALARDEIRKFIS---DSL-DRMTFRIGSNIARDMETLDPVMSDFHFQED 262

  Fly   216 DLWRMDLWGLYNVPII--FQQLEVPLMIVDFKETSVKVQVPLSV-LCDCITIRCVHTDFDHHSPH 277
            |:..|.||.....|:.  :.||   :.::|....|:.:..|.:: |.||: ||.:..:|||||
Mosquito   263 DVLSMYLWSFRPDPLAPDYNQL---MKVIDMVPLSLVLHRPPALDLKDCL-IRGMWLEFDHHS-- 321

  Fly   278 AKSYEPLTVESIFMPNAGLTDMEESVVGEWLMQNDIQEETLNNMNRRREEYDELMQLIAERTEQA 342
              :.:|........|...|...:|:   ||:.:.:::.:.|..:.:.||:||  .:...::.|..
Mosquito   322 --NMDPTHTIPALEPTVELIPAQEA---EWIERQEVKRKRLTALRKLREDYD--AEQCRKQAEAE 379

  Fly   343 AKEAKFGKGGDGDKRPKIVIP-------KTPKTVPLVPQGMYP-----------DVFKEFLFREE 389
            |.||:  |||...|.|....|       |:||..| ||:   |           |:..||..:|.
Mosquito   380 ALEAQ--KGGKDTKTPAAAAPKAGGKKGKSPKQPP-VPE---PEPAVITDETEVDIDAEFERQEA 438

  Fly   390 DQYKKFLSTYFHPDNLSLTPEEVNLRECIIVGGIYNIS----------------FVRRPDQTQF- 437
            |::...|:: ..|....|.|..:||||..||||::.::                :...||..|.
Mosquito   439 DRFWDTLAS-VSPKARPLRPGYINLREYAIVGGVFKLARFDRLPQPMEPRPDFIYTNVPDGLQLT 502

  Fly   438 EKFNIVLHEDGRVLKVIPQVVAKQD----------NRKSRLTEYTRMTLGTSQMKLSEEELPFFV 492
            ||....|..:| ::|:..|:.|...          .|.....::|::|....|..|..:|:....
Mosquito   503 EKGYRALEPEG-LIKIELQLPAHCHWWEEPTVCWWERWEEGEQFTQLTPEVQQFHLQYDEIEAHK 566

  Fly   493 VTV--QLPPH-LCR--WGKPEV--------------CHYLRELQTPTRAPD----RSTLVTLNVL 534
            .|:  ..|.| |.|  .|:|::              .|||.......|.|:    |:.|..|..|
Mosquito   567 ATLLFAAPEHRLSRALVGEPKLVRDFSLMDIPVEVRLHYLIRDHLLPRVPEGYRFRAELNRLYAL 631

  Fly   535 SPIRISSELSKREDGSVQSTLANQFSPPLKSLLKQSITYGHFPLRG-----------------EP 582
            ...|.:...::..:...:..|..::...|.......::....|:..                 :.
Mosquito   632 LTERTARRKAREREQMARDGLVRKYEQFLTDGQDAGLSEMRLPIDSDIDSGDGTDGTEEQDGTDA 696

  Fly   583 IANFNLDKSLNKIEIMKLEK----------MCLPRIISSFKFPSEFVEDQLTSEALKSRPNRLVK 637
            :....:|:.|.:..:...::          :|.|.::......||..   :|:| |......||:
Mosquito   697 LVAQEMDEKLQQFSLAAADEAAHYLHPPVPLCQPLVVGDRYDGSEAA---ITAE-LMQEMEALVR 757

  Fly   638 RLDTETAVEAKTPAEIYFEYESQERPERAFPIFEKTVAIEFSSAAEL--MPSIEC-GNKATACGL 699
            |:::..|:         .:.:|.||..:.|..|  .:.:|:....|.  .|.:.. |.:|...|.
Mosquito   758 RMESTDAM---------LDNDSNERLCKLFSTF--LLLLEYLREKEKPNFPPVPVPGEEAEPAGD 811

  Fly   700 LSTLEDIKEKYLQRPQELLDQIQVQVSKKSEKKAEKWENKNADGRSSAFSFRDRSSFANVNGKKT 764
            :|.        :.:|:.....::::.:||..........:...|.|.|
Mosquito   812 VSA--------MVQPKPRRRWLEIRTTKKYPLGLGAGRTRTLSGVSEA----------------- 851

  Fly   765 ALDAKTKINETEIMITISTSENKMEIPSTSKTRTRRSGSVMKRR-STRKSARMEDMDRFRPMDSE 828
                           ::...|.|      .:.|.:.:|||..:| ||..|...::.:     :.|
Mosquito   852 ---------------SLGQDEKK------KRKRRKSAGSVTAQRDSTALSDAQQEQE-----EQE 890

  Fly   829 PPVLLDH----WTKEYIMESQINLETNTLTFRTDRLGIFGLAFKRYEHFPFRDWCLQPSEDNPD- 888
            ...|::|    |:...|.....:.|...|||.|||||::|||.::|.:.||..|.::......:
Mosquito   891 AMALIEHEPGRWSTMPIRNQSYDPERRLLTFTTDRLGVYGLAARKYCNIPFVHWDMRRHGRIANL 955

  Fly   889 EVILSLDTFHVRMFFYISARGVRGYVTDLVKGYTAKPVKYLE-----IVEPISD----FRELRKL 944
            ...|:|.|..:::.||::|:|.|..:.:..|..|.|  .:||     .|.|..|    ..||.|.
Mosquito   956 TTALTLTTKSLQIVFYVTAQGYRLALQEHAKKQTKK--LFLEEAPAPEVLPPGDGTFTLEELEKF 1018

  Fly   945 LIERNLNIFAENDASYYI--TNGYFSIKHIALELHTYNTMALQCKLMKFCRSSWNRLAQRRDIIV 1007
            |...|:::|.:.|..:|:  .....|.||.::|.|....:.:.|....|....|||.|.||..:|
Mosquito  1019 LQRMNVHLFPQVDTCFYVPGVERAASPKHPSMESHNLRCLGVFCLTHNFQSCLWNRYAHRRTALV 1083

  Fly  1008 ---EMKIAKDNSDYSEVTMRITPEKTTFVKISEMCSDDVNVVKLRYEDTWRNVNNYNDFGQAIYS 1069
               |:...::..::.  |:.|||.|:.||::.|:|||.:..:.|.|... ....:||   ...|.
Mosquito  1084 LGRELIEGRNEPEFG--TVMITPLKSQFVEVEELCSDALEQILLAYHPR-PEEQSYN---ADCYG 1142

  Fly  1070 LNPHTLEGSNK------DAMLFVYLKRLLNEIRPLSYS 1101
            |...:||..::      .|:|...:.:||.:::.||||
Mosquito  1143 LLKDSLEEPSRKVLAKTPALLQWNVGQLLQKLQLLSYS 1180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33287	NP_001137993.1	Casc1_C	835..1053	CDD:432508	71/236 (30%)
LOC11175834	XP_061503625.1	None