Protein Alignment CG33286 and CG12983

DIOPT Version :10

• Sequence 1: NP_001097653.1
• Gene: CG33286 / 2768984
• FlyBaseID: FBgn0053286
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_001137992.1
• Gene: CG12983 / 40319
• FlyBaseID: FBgn0037040
• Length: 1104
• Species: Drosophila melanogaster
• Alignment Length: 1149
• Identity: 418/1149 - (36%)
• Similarity: 639/1149 - (55%)
• Gaps: 132/1149 - (11%)

  Fly     1 MVKRKSTAAA--KPVAEPILRYPLISENEVMDREARYMSRLNDFTVSAELVKGAQRDFYNQEVDR 63
            |||||:..|.  ||..|      |:||.|.|.|...||.||.|...|...:..|..::...:..:
  Fly     1 MVKRKNQDAVSIKPAVE------LLSEEEWMARRNIYMQRLADLKTSVAFIDDAVEEYKELQKQK 59

  Fly    64 MFREHWEHHLRCDGLPRPYLPVEVRTFMSKIRFYDEIETNNSMDWTLSVDERSILTQNIFRVDKT 128
            :..:.|..:|.|||||.|..|.|:|.|:.::.|.::....|.:.|.|||||.|:|:|...|.|:|
  Fly    60 LRNDKWNSYLACDGLPNPSRPAEIRKFIFQLNFMEQESCANEISWVLSVDECSVLSQAPDRCDRT 124

  Fly   129 RRMMMVNKDNPGEHYDHNVQMCLNALKQMDAMLDNEAEMVRMSDKRQKDVIEVYTEVEAEIGDLF 193
            |::|..::.|.|:.||..||..|..::::..:|.|:.|:|.:...:.:::.::..|:..||...|
  Fly   125 RKIMEKSRPNVGQLYDETVQRILATIERVQRVLRNDDELVHLPTFQVRELDKIPNELYGEIESFF 189

  Fly   194 DRLTYRVLSMQDAYMESKDGRVAVWSYTCNPWRLDLWGLRNVPIIFDQLELPVMLAEFSATSVEV 258
            |:|||||:|..||.|.:||..::.:.|.|:.:.|::|||::|||.|:.|:||||.::.:...|.:
  Fly   190 DKLTYRVVSSPDALMMNKDSILSCYCYKCSNFDLEIWGLQDVPIRFNYLKLPVMCSDLNCVGVTI 254

  Fly   259 QIPKSVLKDCVTIRSLHMDFDNISQNAKSFEIAVKASLNYPNAGIVDIENSVVNEWHMQLEIQEE 323
            |:|.|||.|.:|:|.:...||.:|..|||||:.:.:|: .||.|:|||.:||::||..|::|||:
  Fly   255 QLPLSVLCDNLTLRCVRTFFDPLSHLAKSFELVIDSSV-IPNCGLVDIADSVMSEWMTQMDIQED 318

  Fly   324 TLNLMLTRRREYEDMMELIAEKTEQAAKAAKQTDPDKMVKITIPKAPKEPPYVPTGMFPDIYEDF 388
            .:..|.|..|.|.:.:..||:      ..||:....:..||.|||.||.|..:|.|||||..:.|
  Fly   319 LVVKMETEMRAYNEAIAFIAQ------AEAKEKRKSQKKKIAIPKPPKMPQELPAGMFPDPRKIF 377

  Fly   389 LRIEESQYSGYLDEVCHPRHLDMQPFEINLRDYIMLGGIYSIMFIRRPDQTQFEQFNIVLHEDGR 453
            |..|:...:.:.:...||.::::.|.|:|||.:|:||||.|::|:.:.....:|:|||.||||||
  Fly   378 LEHEKRDCTDFFNRYFHPGNINLLPSEVNLRRFIILGGIVSLVFVGKAKHASYEKFNITLHEDGR 442

  Fly   454 V----VHILTE----------MKADIPVEAVRKSNIGRKTRETYRGTKIKLEDDELPYFIVTLQV 504
            |    ::||.|          .|.||..:.:|.:.:|..::     ..:.||.|||||:.:|.:|
  Fly   443 VLRKSLNILDESSTEECSMQPSKLDIGTDIMRDTEVGEASK-----IPLHLEPDELPYYFLTFKV 502

  Fly   505 AADLCKWSEPVVCHFI-TEKDFIPT-------DYKRESYWVPTMQSVIRHSEYAGRSMLNLGSQI 561
            ...||.|.||:||.|. :|.:..|:       |.|.:....|..:|..:.:|...|.....||..
  Fly   503 PNHLCLWGEPIVCQFFESEIEETPSKAKAEELDKKLDKKKKPVRKSSRKENESVLRVPTTSGSVS 567

  Fly   562 SGD------------------SANIFRPSLRSFLRQSKVGAAPKPGVPIEDFKLEK--------- 599
            ..:                  |.||:|||..:.:|||        |:..|..:.:|
  Fly   568 MSEEKPPQSNRPTYHQPARENSVNIYRPSALTIVRQS--------GMETEQIQYKKTFKNSNLVK 624

  Fly   600 -KLSHLEIRTLEKYCLPRIISSFKFPVDFRDEKRE--FIRQGP-RALVKRPDAEEV-VTQVKTLD 659
             .:|...:..|:..||||||||.:||.||:|:|.|  .:::.| ..|.||...|.| .||::...
  Fly   625 EPISKRNLSLLQDQCLPRIISSLRFPRDFQDDKMEAQAMKKIPVTQLYKRQLTESVGSTQIEKFS 689

  Fly   660 FNYNSQVLGPERMYPYFPQMDPIKYPIPFDD--LEPGPVNPTSALELLKTFDNIKSKYQEKHIDL 722
            |||..| ..|||:||.||..:.::......|  .|.|     :.|.||:|.:.||.||.:....:
  Fly   690 FNYEDQ-SNPERLYPKFPVTEDLRVETDRTDSSKEEG-----TMLGLLRTLEGIKDKYLDAPKRI 748

  Fly   723 ISQPDEQDKKSKQKKLGVKEEDDVPEAQIAKRKF-----------------------------SK 758
            :.|.....:.|::     ...|.:|..:..::.:                             |.
  Fly   749 VEQTTHAVRMSRK-----AYSDPIPTTRSRRQSYFGRRSVRQLDSSIMSIARPVDIEYELSETSD 808

  Fly   759 LGDKVRSSVKTDRMDRVTVGSDKSSVKTNPMSEEQVTHWTTKYVKDVVIDRETNSITFKTDRLGL 823
            .|:::..|.|..|:        .|::.:.........||||:::.:...::|:..:..||||||.
  Fly   809 TGEQMIKSRKDSRL--------PSTILSQSAEPRNAAHWTTEFILESSFNKESKVVIVKTDRLGH 865

  Fly   824 LGLAFKRYEHFPFRNWSLQPNEENPDEIILCVDTFHVRIFFYITCKGVRGYVTDLSKGYTAKPIK 888
            .|.|::||.|||||:|.|:.||:|.|||||.:||:|||:.|:|:..|:|.:..|:.|.|..:|.|
  Fly   866 FGFAYRRYAHFPFRHWELEKNEQNHDEIILTLDTYHVRVVFFISKDGIRCHAIDIPKEYVHRPFK 930

  Fly   889 YLEIVEPISDFRQMRQIFISKNINIFAENDASFYIENGYFSMKHVALEMHTYNIMALHCKLMKFY 953
            |::|.:|||||.::|:.....|:|:|||.||.|||:.||||.||:|.|:|.|:.:|:|.|||||.
  Fly   931 YIDIDKPISDFVELRKRLQDMNLNVFAELDACFYIDQGYFSQKHLAAELHIYDAIAVHGKLMKFS 995

  Fly   954 RSSWNRLADRRDIIMGMKIAKDNSDYSEVTMRITPEKTTFVQISENCSDKVNVIVLNYINTWRNI 1018
            ||.|||||..||:::.::..:|..|.||||:|:|||.:|||.:||.|||...||.|||.:||||:
  Fly   996 RSQWNRLAKDRDLVLCLQNTRDIHDGSEVTVRVTPEVSTFVDVSELCSDDTKVIKLNYKSTWRNM 1060

  Fly  1019 GNFTDLHQAINSMVPNATEVRNKDSILLYYVTRMLKEIRLLSFS 1062
            |.::||||.||||.|.||::||:|:..:||:.::|:|||.||||
  Fly  1061 GTYSDLHQLINSMYPQATDMRNRDANQMYYIRQLLQEIRPLSFS 1104

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33286	NP_001097653.1	Casc1_C	793..1014	CDD:432508	111/220 (50%)
CG12983	NP_001137992.1	Casc1_N	17..152	CDD:464947	49/140 (35%)
		Casc1_C	838..1056	CDD:432508	111/217 (51%)