Protein Alignment CG33286 and CG15373

DIOPT Version :10

• Sequence 1: NP_001097653.1
• Gene: CG33286 / 2768984
• FlyBaseID: FBgn0053286
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_001097013.2
• Gene: CG15373 / 32784
• FlyBaseID: FBgn0030889
• Length: 1162
• Species: Drosophila melanogaster
• Alignment Length: 1207
• Identity: 254/1207 - (21%)
• Similarity: 452/1207 - (37%)
• Gaps: 274/1207 - (22%)

  Fly    25 ENEVMDREARYMSRLNDFTVSAELVK---GAQRDFYNQEVDRMFREHWEHHLRCDGLPRPYLPVE 86
            :.||.:...| .|:|.|..:..:.|:   .|.:|....|.|      ||..:||:|||....|.:
  Fly    57 QQEVAENRQR-RSQLKDSMLFFDAVRTAIEAIKDGERHERD------WEKFMRCNGLPNAASPSD 114

  Fly    87 VRTFMSKIRFYDEIETNN--SMDWTLSVDERSILTQNIFRVDKTRRMMMVNKDNPGEHYDHNVQM 149
            :|.::.  :::.:|...:  |.:|.|..|||::|||:....|.||..:...:...|:.|.|.::.
  Fly   115 LRKYIH--QWHTDIAKRHLESRNWLLRTDERTLLTQDAQVPDLTRISLRQQQGRLGDVYAHRIKE 177

  Fly   150 CLNALKQMDAMLDNEAEMVRMSDKRQKDVIEVYTEVEAEIGDLFDRLTYRVLSMQDAYMESKDGR 214
            .|..|.::|.||..:.:...::    .|::::.||:...:....|..||:.:|..:..||.....
  Fly   178 VLGILNELDEMLPFKQKSALIA----ADLVKLKTEMRVFLKQHLDEFTYKTMSHIERDMEIDRPG 238

  Fly   215 VAVWSYTCNPWRLDLWGLRNVPIIFDQLELPVMLAE--------FSATSVEVQIPKSVLKDCVTI 271
            |:...|:.:.::..:|.......|  .|.....:.|        |....:::.:|.:|......:
  Fly   239 VSKHIYSSDVFQSFVWTFSKDAQI--SLNPKARIGEQSSHNEIDFPTIEMQISLPPTVHLQSSAL 301

  Fly   272 RSLHMDFDNISQNAKSFEIAVKASLNYPNAGIVDIENSVVNEWHMQLEIQEETLNLMLTRRREYE 336
            |.|.:::|:.|....|:      .|.:..:...:|......||..:.||    |..||.......
  Fly   302 RGLWLNYDHFSDYCSSY------CLKHARSANANILRQTKREWRKRKEI----LQAMLDDCGREI 356

  Fly   337 DMMELIAEKTEQAAKAAKQTDPDKMVKITIPKAPKEPPYVPTGMFPDIYEDFLRIEESQYSGYLD 401
            .:.|| .:.|:....|:.|             .|:|..|....::.: |||.|.....:..|
  Fly   357 PLSEL-EQLTQDQHSASSQ-------------PPRERTYDVDKLYAE-YEDELSKAHRRAIG--- 403

  Fly   402 EVCHPRHLDMQPFEINLRDYIMLGGIYSIMFIRRPDQTQFEQFNIVLHEDGRVVHILTEMKADIP 466
                |....|...::|||.|.::||:|.|.|:..|.|.:                   ::.|...
  Fly   404 ----PEAYGMLETDVNLRKYRIIGGVYCIDFLETPQQDK-------------------QLNARSF 445

  Fly   467 VEAVRKSN--IGRKTRETYR-------GTK------------IKLEDDELPYFIVTLQVAADLCK 510
            :..:..:|  :.::..:||:       |.:            |:...|:|.  :||||:...:..
  Fly   446 IRTITSANSLVHKEYYQTYKPPPPVLPGVRRLPEEIEAEMRMIEAALDKLA--LVTLQLPDSVIW 508

  Fly   511 WSEPVVCHFITEKDFIPTDYKRESYWVPTMQSVIRHSEYAGRSMLNLGSQISGDSA--------- 566
            :..||.|.:.|..:.:      |......|:..::.....|....:....:||.:|
  Fly   509 FEPPVACRWETNVETL------EMELADGMKPEVQKPHGEGDGEADGTGAVSGTAAATTATPTEA 567

  Fly   567 ----NIFRPS-----------LRSFLRQSKVGAAPKPGV--PIEDFKLEKKLSHLEIRTLEK-YC 613
                ...:||           :||  ::|.:|...:..|  .|.||.|....|.:::..|.| :.
  Fly   568 TPLSTHAQPSPLKSSPRCPARMRS--QKSDIGGESRQQVLREINDFDLRAIPSDVDLYGLVKDFV 630

  Fly   614 LPRIISSF------KFPV---DFRDEKREFI-RQGPRALVKRPDAE----EVVTQVKTLDFNYNS 664
            :||:...|      ..||   ..|..|..|: ||....|.:..|..    |:..:::.|..| :.
  Fly   631 VPRLPQGFCVRLEQSTPVMSTGLRQRKVMFLARQAHIRLGQGKDMADDQLEIPKELQRLQLN-SK 694

  Fly   665 QVLG--------PERMYP--------YFPQMDP-----------------------IKYPIPFDD 690
            ..||        |..|:|        .|.||.|                       .:..:|.|.
  Fly   695 PGLGAEFLDTEEPAEMFPPLCFDKLLKFRQMAPRSRGPAHLQGYLFSQLIDDMDRLWRLQLPRDQ 759

  Fly   691 -------------------LEPGPVNPTSALELLKTFDNIKSKYQE------------------- 717
                               .|||...|..........:|::...||
  Fly   760 QEEIIQQISEQLSPTGSRTSEPGEKEPRETENDGDLAENMQPLSQELVDVLQPATAAAAFAYYTG 824

  Fly   718 ----KHIDLISQPDEQDKKSKQKKLGVKEEDD------VPEAQIAKRKFSKLGDKVRSSVKTDRM 772
                :...|.::|:.:....:...:...|:||      |...:.|....:.|.|.:..:..:|..
  Fly   825 ISFVRDSQLPAEPEPESSAKRSNSMDSSEDDDDDVDSLVELLEGASTAANTLHDLLGPATNSDNS 889

  Fly   773 DRVTVGSDKSSVKTNPMSEEQVTHWTTKYVKDVVIDRETNSITFKTDRLGLLGLAFKRYEHFPFR 837
            |      .:|..|.:.::......|:|:.|.|...:.:..||.|:|.|||:.|.|..:|.:.|::
  Fly   890 D------SESKQKMSNVAAITQGKWSTRDVHDTKFNEDKLSIQFRTGRLGIFGFALNKYSNMPYQ 948

  Fly   838 NWSLQPNEENPDEIILCVDTFHVRIFFYITCKG--VRGYVTDLSKGYTAKPIKYLEIVEPISDFR 900
            .|.|:|:.:||..||.......:.:...||..|  |..:....::|.|....|.|.:.|
  Fly   949 TWDLRPDMKNPGTIIFSFTASLISLDMTITKSGYTVNNFQGGSTQGITDMIGKTLSLSE------ 1007

  Fly   901 QMRQIFISKNINIFAENDASFYIENGYFSMKHVALEMHTYNIMALHCKLMKFYRSSWNRLADR-- 963
             ::...|...::||.:.||..|.|..  ..|:..:|||.|..::...:...|..|.||.||..
  Fly  1008 -LKATLILSAVDIFPDEDAFCYTEGS--CEKNYVMEMHCYACLSTLAQSHNFSWSRWNLLAGSRT 1069

  Fly   964 -----RDIIMGMKIAKDNSDYSEVTMRITPEKTTFVQISENCSDKVNVIVLNYINTWRNIGNFTD 1023
                 |::|.|.|:..    ||  |:.:||.||:.:..:| .|...|.:.:..:..:.::...:.
  Fly  1070 AVLLVRELIEGKKVPY----YS--TLLVTPLKTSIIDCTE-VSASFNAVGIPGMEYYADLYQLSQ 1127

  Fly  1024 LHQAINSMVPNATEVRNKDSILLYYVTRMLKEIRLLS 1060
            .|....|:    .:.|..:.:|...|.::|..||.||
  Fly  1128 AHAQPGSL----EKQRTMNPVLRDNVAKILMAIRPLS 1160

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33286	NP_001097653.1	Casc1_C	793..1014	CDD:432508	63/229 (28%)
CG15373	NP_001097013.2	Casc1_N	14..>126	CDD:464947	20/77 (26%)
		Casc1_C	908..1104	CDD:432508	61/211 (29%)