Protein Alignment CG33286 and CG33287

DIOPT Version :10

• Sequence 1: NP_001097653.1
• Gene: CG33286 / 2768984
• FlyBaseID: FBgn0053286
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_001137993.1
• Gene: CG33287 / 2768986
• FlyBaseID: FBgn0053287
• Length: 1101
• Species: Drosophila melanogaster
• Alignment Length: 1129
• Identity: 552/1129 - (48%)
• Similarity: 742/1129 - (65%)
• Gaps: 95/1129 - (8%)

  Fly     1 MVKRKSTAAAKPVAEPILRYPLISENEVMDREARYMSRLNDFTVSAELVKGAQRDFYNQEVDRMF 65
            |.|...|....||        ||||.|:|:|:..|.:|::|...:....:.:...|...|.:|..
  Fly     1 MGKEGGTTTETPV--------LISEAEMMERQKNYTTRMHDIAAACATFRKSLLQFRLLEEERTN 57

  Fly    66 REHWEHHLRCDGLPRPYLPVEVRTFMSKIRFYDEIETNNSMDWTLSVDERSILTQNIFRVDKTRR 130
            :..|:.:|||||||:...|:|:|||::|||.::||||.||:|||:.|||||:|:|||::.|.||.
  Fly    58 QGRWDQYLRCDGLPKVRSPIEIRTFLAKIRHFEEIETKNSIDWTMGVDERSVLSQNIYQKDLTRP 122

  Fly   131 MMM-VNKDNPGEHYDHNVQMCLNALKQMDAMLDNEAEMVRMSDKRQKDVIEVYTEVEAEIGDLFD 194
            ::. ...||||.:::.|::.|::.|:|:|.::|||.||.||:.....|::|||.:|:.||..|||
  Fly   123 VLQRTAVDNPGSYFESNLKKCMDVLQQVDILMDNEVEMERMNKSVLVDLLEVYRDVQLEIESLFD 187

  Fly   195 RLTYRVLSMQDAYMESKDGRVAVWSYTCNPWRLDLWGLRNVPIIFDQLELPVMLAEFSATSVEVQ 259
            |||||:|.||.|||||.:|.||.||::|:.||:|||||.||||||.|||:|:|:.:|..|||:||
  Fly   188 RLTYRILRMQKAYMESVNGIVARWSHSCDLWRMDLWGLYNVPIIFQQLEVPLMIVDFKETSVKVQ 252

  Fly   260 IPKSVLKDCVTIRSLHMDFDNISQNAKSFEIAVKASLNYPNAGIVDIENSVVNEWHMQLEIQEET 324
            :|.|||.||:|||.:|.|||:.|.:|||:|.....|:..||||:.|:|.|||.||.||.:|||||
  Fly   253 VPLSVLCDCITIRCVHTDFDHHSPHAKSYEPLTVESIFMPNAGLTDMEESVVGEWLMQNDIQEET 317

  Fly   325 LNLMLTRRREYEDMMELIAEKTEQAAKAA---KQTDPDKMVKITIPKAPKEPPYVPTGMFPDIYE 386
            ||.|..||.||:::|:||||:||||||.|   |..|.||..||.|||.||..|.||.||:||:::
  Fly   318 LNNMNRRREEYDELMQLIAERTEQAAKEAKFGKGGDGDKRPKIVIPKTPKTVPLVPQGMYPDVFK 382

  Fly   387 DFLRIEESQYSGYLDEVCHPRHLDMQPFEINLRDYIMLGGIYSIMFIRRPDQTQFEQFNIVLHED 451
            :||..||.||..:|....||.:|.:.|.|:|||:.|::||||:|.|:|||||||||:||||||||
  Fly   383 EFLFREEDQYKKFLSTYFHPDNLSLTPEEVNLRECIIVGGIYNISFVRRPDQTQFEKFNIVLHED 447

  Fly   452 GRVVHILTEMKADIPVEAVRKSNIGRKTRETYRGTKIKLEDDELPYFIVTLQVAADLCKWSEPVV 516
            |||:.::.::.|.   :..|||.:...||.|...:::||.::|||:|:||:|:...||:|.:|.|
  Fly   448 GRVLKVIPQVVAK---QDNRKSRLTEYTRMTLGTSQMKLSEEELPFFVVTVQLPPHLCRWGKPEV 509

  Fly   517 CHFITEKDFIPTDYKRESYWVP-TMQSVIR-HSEYAGRSMLNLGSQISGDSANIFRPSLRSFLRQ 579
            ||::.|.. .||.....|..|. .:.|.|| .||.:.|.    ...:....||.|.|.|:|.|:|
  Fly   510 CHYLRELQ-TPTRAPDRSTLVTLNVLSPIRISSELSKRE----DGSVQSTLANQFSPPLKSLLKQ 569

  Fly   580 S-KVGAAPKPGVPIEDFKLEKKLSHLEIRTLEKYCLPRIISSFKFPVDFRDEK--REFIRQGPRA 641
            | ..|..|..|.||.:|.|:|.|:.:||..|||.||||||||||||.:|.:::  .|.::..|..
  Fly   570 SITYGHFPLRGEPIANFNLDKSLNKIEIMKLEKMCLPRIISSFKFPSEFVEDQLTSEALKSRPNR 634

  Fly   642 LVKRPDAEEVVTQVKT---LDFNYNSQVLGPERMYPYFPQMDPIKYPIPFD---DLEPGPVNPTS 700
            ||||.|.|..| :.||   :.|.|.||. .|||.:|.|.:...|::....:   .:|.|  |..:
  Fly   635 LVKRLDTETAV-EAKTPAEIYFEYESQE-RPERAFPIFEKTVAIEFSSAAELMPSIECG--NKAT 695

  Fly   701 ALELLKTFDNIKSKYQEKHIDLISQPDEQ-DKKSKQ----------------------------- 735
            |..||.|.::||.||.::..:|:.|...| .|||::
  Fly   696 ACGLLSTLEDIKEKYLQRPQELLDQIQVQVSKKSEKKAEKWENKNADGRSSAFSFRDRSSFANVN 760

  Fly   736 -KKLGVKEEDDVPEAQI----------------AKRKFSKLGD--KVRSSVKTDRMDRVTVGSDK 781
             ||..:..:..:.|.:|                :|.:..:.|.  |.||:.|:.||:.:.
  Fly   761 GKKTALDAKTKINETEIMITISTSENKMEIPSTSKTRTRRSGSVMKRRSTRKSARMEDMD----- 820

  Fly   782 SSVKTNPMSEEQ---VTHWTTKYVKDVVIDRETNSITFKTDRLGLLGLAFKRYEHFPFRNWSLQP 843
               :..||..|.   :.|||.:|:.:..|:.|||::||:|||||:.|||||||||||||:|.|||
  Fly   821 ---RFRPMDSEPPVLLDHWTKEYIMESQINLETNTLTFRTDRLGIFGLAFKRYEHFPFRDWCLQP 882

  Fly   844 NEENPDEIILCVDTFHVRIFFYITCKGVRGYVTDLSKGYTAKPIKYLEIVEPISDFRQMRQIFIS 908
            :|:||||:||.:||||||:||||:.:|||||||||.|||||||:|||||||||||||::|::.|.
  Fly   883 SEDNPDEVILSLDTFHVRMFFYISARGVRGYVTDLVKGYTAKPVKYLEIVEPISDFRELRKLLIE 947

  Fly   909 KNINIFAENDASFYIENGYFSMKHVALEMHTYNIMALHCKLMKFYRSSWNRLADRRDIIMGMKIA 973
            :|:|||||||||:||.|||||:||:|||:||||.|||.||||||.||||||||.|||||:.||||
  Fly   948 RNLNIFAENDASYYITNGYFSIKHIALELHTYNTMALQCKLMKFCRSSWNRLAQRRDIIVEMKIA 1012

  Fly   974 KDNSDYSEVTMRITPEKTTFVQISENCSDKVNVIVLNYINTWRNIGNFTDLHQAINSMVPNATEV 1038
            |||||||||||||||||||||:|||.|||.|||:.|.|.:||||:.|:.|..|||.|:.|:..|.
  Fly  1013 KDNSDYSEVTMRITPEKTTFVKISEMCSDDVNVVKLRYEDTWRNVNNYNDFGQAIYSLNPHTLEG 1077

  Fly  1039 RNKDSILLYYVTRMLKEIRLLSFS 1062
            .|||::|..|:.|:|.|||.||:|
  Fly  1078 SNKDAMLFVYLKRLLNEIRPLSYS 1101

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33286	NP_001097653.1	Casc1_C	793..1014	CDD:432508	164/223 (74%)
CG33287	NP_001137993.1	Casc1_C	835..1053	CDD:432508	164/217 (76%)