DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trl and Zbtb9

DIOPT Version :9

Sequence 1:	NP_001261846.1	Gene:	Trl / 2768981	FlyBaseID:	FBgn0013263	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_001005916.1	Gene:	Zbtb9 / 474156	MGIID:	1918022	Length:	459	Species:	Mus musculus

Alignment Length:	434	Identity:	84/434 - (19%)
Similarity:	148/434 - (34%)	Gaps:	112/434 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLLD--LLKNTPCKHPVVMLAGV 78
            :.:||:.::...|..|...|.:|...||...|||.||.||||:..|  ||.:.|   .:.:...:
Mouse    30 HSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKLLLGDAP---RLTLPNVI 91

  Fly    79 NANDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGLAPQTVTKDDYTTHSIQLQHMIPQHHD 143
            .|:..|.||:.:|.|.:.:....||:.|..|..|.:.    |.|.:.......::....|
Mouse    92 EADAFEGLLQLIYSGSLHLPLDALPAHLLVASGLQMW----QVVDRCSEILRELETSGGI----- 147

  Fly   144 QDQLIATIATAPQQTVHAQVVEDIHHQGQILQATTQTN----AAGQQQTIVTTDAAKHDQAVIQA 204
                     :|..:.....::......|..::::...|    :|..:.:::....|..:.:.::.
Mouse   148 ---------SAGGRASSLTLISTTSSGGWCIRSSPFQNPVRSSASTENSVLPESPAGGEGSELEG 203

  Fly   205 FLPARKRKPRVKKMSPTAPKISKVEGMDTIMGTPTSSHGSGSVQQVLGENGAEGQLLSSTPIIKS 269
            .|..:.:....::....||          :..||.....||.|.|..|.:..      .||.:.|
Mouse   204 MLQIQVKVEEEEEQGSAAP----------LFQTPQPERVSGGVSQACGSHPL------PTPALPS 252

  Fly   270 EGQKVETIVTMDPNNMIPVTSANAATGEITPAQGATGSSGGNTSGVLSTPKAKRAKHPPGTEKPR 334
            :..:.|: .|:||                 ||                         ||
Mouse   253 KPSEDES-STVDP-----------------PA-------------------------PP------ 268

  Fly   335 SRSQSEQPATCPICYAVIRQSRNLRRHLELRHFAKPGVKKEKKSKSGNDTTLDSSMEMNTTAEGD 399
              .|:.|     |.|  :.|     .::|.:.....|.|::.|..||.|:.....:....::
Mouse   269 --VQASQ-----ILY--VNQ-----ENVECKEEIARGTKEKTKVLSGEDSEEKEELRYLLSS--- 316

  Fly   400 NTVGSDGAGGAGSAGGQSSATSGKKSSSGSSGSGSGALSSSGSV 443
               |...:.|||....:.....|.:..||..|.|....:..|.|
Mouse   317 ---GGGESSGAGDPSWKPVDLHGNEILSGDGGPGGTGQAMHGPV 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trl	NP_001261846.1	BTB	27..117	CDD:279045	30/91 (33%)
		BTB	35..118	CDD:197585	28/84 (33%)
		GAGA	319..372	CDD:150045	8/52 (15%)
Zbtb9	NP_001005916.1	BTB	38..138	CDD:279045	32/106 (30%)
		BTB	49..142	CDD:197585	30/99 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	178..200		2/21 (10%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..274		22/133 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	293..356		14/68 (21%)
		C2H2 Zn finger	374..391	CDD:275368
		C2H2 Zn finger	399..419	CDD:275368
		zf-C2H2	399..419	CDD:278523
		C2H2 Zn finger	426..443	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910