DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trl and Zbtb39

DIOPT Version :9

Sequence 1:	NP_001261846.1	Gene:	Trl / 2768981	FlyBaseID:	FBgn0013263	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_001124009.1	Gene:	Zbtb39 / 299510	RGDID:	1306532	Length:	711	Species:	Rattus norvegicus

Alignment Length:	326	Identity:	69/326 - (21%)
Similarity:	118/326 - (36%)	Gaps:	84/326 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MNSLYSLTWGDYGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLLDLLKNTPCK 69
            |.....|...::..:|:..:...|....:.|.|:..|.|||||||.||..|:.:..:|..||
  Rat     1 MGMRIKLQSSNHPNNLLKELNKCRLSETMCDVTIVVGSRSFPAHKAVLACAAGYFQNLFLNT--- 62

  Fly    70 HPVVMLAGVNA-----------NDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGL---APQ 120
                   |::|           .:.|.:|.|||..|:..|...:..:.:.|:.|.::.|   ...
  Rat    63 -------GLDAARTYVVDFITPANFEKILSFVYTSELFTDLINVGVIYEVAERLGMEDLLRACHS 120

  Fly   121 TVTKDDYTTHSIQLQHMIPQHHDQDQLIATIATAPQQTVHAQVVEDIH----------HQGQILQ 175
            |....:.||.:              :.:.:.:.:|..|:....|:..|          |.|....
  Rat   121 TFPDLESTTIA--------------KSLTSTSDSPCVTLSCPSVDPTHPLGELRGSGEHFGPDRN 171

  Fly   176 ATTQTNAAG---QQQTIVTTDAAKHDQAVIQAFLPARKRKPRVKKMSPTAPKISKVEGMDT---I 234
            ....|:|.|   :::..:..| ..|...:.|..||     |:.:......| .:.|..|.|   :
  Rat   172 YALPTDAGGSYKEEERAIAGD-TNHSLPLPQVPLP-----PKSEDHDAPVP-FTSVPSMVTPPPV 229

  Fly   235 MGTPTSSHGSGSVQQVLGENGAEGQLLSSTPIIKSEGQKVETIVTMDPNNMIPVTSANAATGEIT 299
            :||.::              |.:....||     .:..||::......:|..  ||.||.  :||
  Rat   230 LGTVST--------------GIQTSTTSS-----CQPYKVQSNGDFGKSNFF--TSDNAL--DIT 271

  Fly   300 P 300
            |
  Rat   272 P 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trl	NP_001261846.1	BTB	27..117	CDD:279045	28/100 (28%)
		BTB	35..118	CDD:197585	28/96 (29%)
		GAGA	319..372	CDD:150045
Zbtb39	NP_001124009.1	BTB_POZ_ZBTB39	4..126	CDD:349533	32/131 (24%)
		C2H2 Zn finger	344..365	CDD:275368
		C2H2 Zn finger	373..393	CDD:275368
		C2H2 Zn finger	401..419	CDD:275368
		C2H2 Zn finger	452..473	CDD:275368
		C2H2 Zn finger	481..501	CDD:275368
		C2H2 Zn finger	509..529	CDD:275368
		C2H2 Zn finger	539..559	CDD:275368
		zf-C2H2	604..626	CDD:395048
		C2H2 Zn finger	606..626	CDD:275368
		zf-H2C2_2	618..642	CDD:404364
		C1	620..>667	CDD:412127
		C2H2 Zn finger	634..654	CDD:275368
		C2H2 Zn finger	662..682	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000