Protein Alignment Trl and ZBTB38

DIOPT Version :9

• Sequence 1: NP_001261846.1
• Gene: Trl / 2768981
• FlyBaseID: FBgn0013263
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_005247313.1
• Gene: ZBTB38 / 253461
• HGNCID: 26636
• Length: 1196
• Species: Homo sapiens
• Alignment Length: 473
• Identity: 89/473 - (18%)
• Similarity: 167/473 - (35%)
• Gaps: 102/473 - (21%)

  Fly    16 YGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLLDLLKNTPCKHPVVMLAGV-N 79
            :..:::|.:...|..|.|.|.|:......|.||..||.|:|.:    .||....|.:.:.:.| .
Human    16 HSDTVLSILNEQRIRGILCDVTIIVEDTKFKAHSNVLAASSLY----FKNIFWSHTICISSHVLE 76

  Fly    80 ANDLEA-----LLEFVYRGEVSVDHAQ-LPSLLQAAQCLNIQGLAPQTVTKDDY----------- 127
            .:||:|     :|.::|...|.|...: :..|..|.:.|.|..|  :.:|..::
Human    77 LDDLKAEVFTEILNYIYSSTVVVKRQETVTDLAAAGKKLGISFL--EDLTDRNFSNSPGPYVFCI 139

  Fly   128 TTHSIQLQHMIPQHHDQDQLIATIATAPQQTVHAQVVE-----------DIHHQGQILQATTQTN 181
            |...:..:....:.|::    ..|...|:.|....::|           |:....:.:..:.:|.
Human   140 TEKGVVKEEKNEKRHEE----PAITNGPRITNAFSIIETENSNNMFSPLDLRASFKKVSDSMRTA 200

  Fly   182 AAGQQQTIVTTDA------AKHDQAVIQAFLPARKRKPRVKKMSPTAPKISKVEGMDTIMGTPTS 240
            :...::|.|..:|      |:|..|| .:...|.:.:| |::...::|..:..|..:.:...|.:
Human   201 SLCLERTDVCHEAEPVRTLAEHSYAV-SSVAEAYRSQP-VREHDGSSPGNTGKENCEALAAKPKT 263

  Fly   241 SHGSGSVQQVLGENGAEGQL----LSSTPIIKSEGQKVETIVT--MDPNNMIPVTSANAATGEIT 299
            .....:.......:.|...:    :|:..:.:....:...::|  ..|||...|..:.....:.:
Human   264 CRKPKTFSIPQDSDSATENIPPPPVSNLEVNQERSPQPAAVLTRSKSPNNEGDVHFSREDENQSS 328

  Fly   300 PAQGATG-------------SSGGNTSGVLSTPKAKRAKHPPGTEKPRSRSQSEQPATCPICYAV 351
            ...|...             |...::|.:||   |....|.|          :::|..|..|...
Human   329 DVPGPPAAEVPPLVYNCSCCSKAFDSSTLLS---AHMQLHKP----------TQEPLVCKYCNKQ 380

  Fly   352 IRQSRNLRRHLEL----RHFAKPGVKKEKKSKSGNDTTLDSSMEMNTTAEGDNTVGSDGAGGAGS 412
            ......|.||.::    .|...||         ||...|          |...|:|.:|....|.
Human   381 FTTLNRLDRHEQICMRSSHMPIPG---------GNQRFL----------ENYPTIGQNGGSFTGP 426

  Fly   413 AGGQSSATSGKKSSSGSS 430
            ....|....|:.||:||:
Human   427 EPLLSENRIGEFSSTGST 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trl	NP_001261846.1	BTB	27..117	CDD:279045	27/96 (28%)
		BTB	35..118	CDD:197585	24/89 (27%)
		GAGA	319..372	CDD:150045	11/56 (20%)
ZBTB38	XP_005247313.1	BTB	24..123	CDD:279045	28/104 (27%)
		BTB	35..131	CDD:197585	26/101 (26%)
		C2H2 Zn finger	345..365	CDD:275368	5/22 (23%)
		C2H2 Zn finger	374..393	CDD:275368	5/18 (28%)
		C2H2 Zn finger	463..483	CDD:275368
		C2H2 Zn finger	491..511	CDD:275368
		C2H2 Zn finger	519..537	CDD:275368
		C2H2 Zn finger	1013..1033	CDD:275368
		zf-H2C2_2	1026..1049	CDD:290200
		zf-C2H2	1039..1061	CDD:278523
		C2H2 Zn finger	1041..1061	CDD:275368
		zf-H2C2_2	1053..1077	CDD:290200
		C2H2 Zn finger	1069..1089	CDD:275368
		zf-H2C2_2	1082..1106	CDD:290200
		C2H2 Zn finger	1097..1121	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000