DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trl and Zbtb16

DIOPT Version :9

Sequence 1:	NP_001261846.1	Gene:	Trl / 2768981	FlyBaseID:	FBgn0013263	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_001028496.1	Gene:	Zbtb16 / 235320	MGIID:	103222	Length:	673	Species:	Mus musculus

Alignment Length:	382	Identity:	77/382 - (20%)
Similarity:	128/382 - (33%)	Gaps:	109/382 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSLPMNSLYSLTWGDYGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLLDLLKN 65
            |.|....:..|....:.|.|:.....:|..|.|.|..:....:.|.||:.||...|. :.::|.:
Mouse     1 MDLTKMGMIQLQNPSHPTGLLCKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSK-MFEILFH 64

  Fly    66 TPCKHPVVMLAGVNANDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGLAPQTV-------T 123
            ...:|  ..|..::....:.:||:.|...:......|..||.||:.|.|:.|..|.:       .
Mouse    65 RNSQH--YTLDFLSPKTFQQILEYAYTATLQAKAEDLDDLLYAAEILEIEYLEEQCLKILETIQA 127

  Fly   124 KDDYTTHSIQ---------------LQHM-IPQHHDQDQLIATIA--TAPQQTVHAQ-------- 162
            .||..|.:..               |::: |.:|..::...|::|  :.|...|...
Mouse   128 SDDNDTEATMADGGGEEEEDRKARYLKNIFISKHSSEESGYASVAGQSLPGPMVDQSPSVSTSFG 192

  Fly   163 ---------VVEDIHHQGQ-ILQATTQTNAAGQQQTIVTTDAAKHDQAVIQAFLPARKRKPRVKK 217
                     .|:.:...|| :||.|.|..|..::.|                 |....|.|.|.:
Mouse   193 LSAMSPTKAAVDSLMSIGQSLLQGTLQPPAGPEEPT-----------------LAGGGRHPGVAE 240

  Fly   218 MSPTAPKISKVEGMDTIMGTPTSSHGSGSVQQVLGENGAEGQLLSSTPIIKSEGQKVETIVTMDP 282
            :.....::.:..|.|: .|...||. ||.:...|.|...||                       |
Mouse   241 VKMEMMQVDEAPGQDS-PGAAESSI-SGGMGDKLEERSKEG-----------------------P 280

  Fly   283 NNMIPVTSANAATGEITPAQGATGSS------GGNTSGVLSTPKAKRAKHPPGTEKP 333
            .               ||.:|:..:|      |...||...:|..:..:.|||.::|
Mouse   281 G---------------TPTRGSVITSARELHYGREESGEQLSPPVEAGQGPPGRQEP 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trl	NP_001261846.1	BTB	27..117	CDD:279045	23/89 (26%)
		BTB	35..118	CDD:197585	20/82 (24%)
		GAGA	319..372	CDD:150045	5/15 (33%)
Zbtb16	NP_001028496.1	BTB_POZ_ZBTB16_PLZF	16..122	CDD:349514	27/108 (25%)
		C2H2 Zn finger	406..426	CDD:275368
		C2H2 Zn finger	434..454	CDD:275368
		COG5048	<448..622	CDD:227381
		C2H2 Zn finger	463..483	CDD:275368
		C2H2 Zn finger	492..512	CDD:275368
		C2H2 Zn finger	520..540	CDD:275368
		C2H2 Zn finger	548..568	CDD:275368
		C2H2 Zn finger	576..596	CDD:275368
		C2H2 Zn finger	604..624	CDD:275368
		C2H2 Zn finger	632..652	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000