DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trl and Zbtb44

DIOPT Version :9

Sequence 1:	NP_001261846.1	Gene:	Trl / 2768981	FlyBaseID:	FBgn0013263	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	XP_006510278.1	Gene:	Zbtb44 / 235132	MGIID:	1925123	Length:	616	Species:	Mus musculus

Alignment Length:	450	Identity:	88/450 - (19%)
Similarity:	158/450 - (35%)	Gaps:	131/450 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 YGTSLVSAIQLLRCHGDLVDCTLAAGGRSFPAHKIVLCAASPFLLDLL--------KNTPCKHPV 72
            :...::..:.:||..|...|.|:....:.|.|||:||.|.|.|....|        ||      |
Mouse    13 HSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQTEDENKN------V 71

  Fly    73 VMLAGVNANDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGLAPQTVTKDDYTTHSIQLQHM 137
            :.|..|.......|||:.|...:|::...:..:|.||..:.:..:|.   |..::...||
Mouse    72 LDLHHVTVTGFIPLLEYAYTATLSINTENIIDVLAAASYMQMFSVAS---TCSEFMKSSI----- 128

  Fly   138 IPQHHDQDQLIATIATAPQQTVHAQVVEDIHHQGQILQATTQTNAAGQQQTI--VTTDAAKHDQA 200
                     |..|..:.|::::.|         ||  :.::..|...:..:|  |:::.:..::.
Mouse   129 ---------LWNTPNSQPEKSLDA---------GQ--ENSSNCNFTSRDGSISPVSSECSAVERT 173

  Fly   201 VIQAFLPARKRKPRVKKMSPTAP-KIS------------------KVEGMDTIMGTP-TSSHGSG 245
            :.......||||..: .|||.:| |.|                  :.:.:|:.:..| |...|..
Mouse   174 IPVCRESRRKRKSYI-VMSPESPVKCSTQTSSPQVLNSSASYAENRSQPVDSSLAFPWTFPFGID 237

  Fly   246 SVQQVLGENGAEGQLLSSTPIIKSEGQKVETIVTMDPNNMI------------------------ 286
            ...|......||.......|.....|::|...||.:.....
Mouse   238 RRIQPEKAKQAENTRTLELPGPSEAGRRVADYVTCESTKPTLPLGTEEDVRVKVERLSDEEVHEE 302

  Fly   287 ---PVTSANAATGE---------------ITPAQGATGS-SGGNTSGV------LST-------P 319
               ||:::.::..:               |:|...:.|| ..|.|.|:      .||       .
Mouse   303 VSQPVSASQSSLSDQQTVPGSEPVQEDLLISPQSSSIGSVDEGVTEGLPTLQSTSSTNAHADDDD 367

  Fly   320 KAKRAKHP---------PGTEKPRSRSQSEQPATCPICYAVIRQSRNLRRHLELRHFAKP 370
            :.:..::|         ..||:| |.:..::|..||.|.....:.:||::|:.:....||
Mouse   368 RLENVQYPYQLYIAPSTSSTERP-SPNGPDRPFQCPTCGVRFTRIQNLKQHMLIHSGIKP 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trl	NP_001261846.1	BTB	27..117	CDD:279045	28/97 (29%)
		BTB	35..118	CDD:197585	25/90 (28%)
		GAGA	319..372	CDD:150045	13/60 (22%)
Zbtb44	XP_006510278.1	BTB_POZ_ZBTB44	15..130	CDD:349537	32/137 (23%)
		zf-C2H2	399..421	CDD:333835	6/21 (29%)
		C2H2 Zn finger	401..421	CDD:275368	6/19 (32%)
		zf-H2C2_2	413..438	CDD:372612	4/13 (31%)
		C2H2 Zn finger	429..449	CDD:275368
		C2H2 Zn finger	457..476	CDD:275368
		zf-C2H2	487..508	CDD:333835
		C2H2 Zn finger	489..511	CDD:275371
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000