Protein Alignment Trl and rib

DIOPT Version :10

• Sequence 1: NP_001261846.1
• Gene: Trl / 2768981
• FlyBaseID: FBgn0013263
• Length: 623
• Species: Drosophila melanogaster
• Sequence 2: XP_061513904.1
• Gene: rib / 1280759
• VectorBaseID: AGAMI1_010303
• Length: 874
• Species: Anopheles gambiae
• Alignment Length: 804
• Identity: 161/804 - (20%)
• Similarity: 260/804 - (32%)
• Gaps: 267/804 - (33%)

  Fly     9 YSLTWGDYGTSLVSAIQLL---RCHGDLVDCTLAAGGR-SFPAHKIVLCAASPFLLDLLKNTPCK 69
            |.|.|.::.::||..:..|   .|:   ||||:....: .|.||::||.|.||:...:|::.|..
Mosquito     9 YCLRWNNHKSNLVEILDALIKMECY---VDCTIYVDDQVQFKAHRVVLAANSPYFQSILQDVPMD 70

  Fly    70 HPVVMLAGVNANDLEALLEFVYRGEVSVDHAQLPSLLQAAQCLNIQGLAPQTVTKDDYTTHSIQL 134
            |..::..||...::.||||::|.|||:|..||:|.:::.|:.|.::||......|..::
Mosquito    71 HCSILFPGVQEFEMRALLEYMYTGEVNVTQAQIPRIMKIAEQLEVKGLYDMADLKGRFS------ 129

  Fly   135 QHMIPQHHDQDQLIATIATAPQQTVHAQVVEDIHHQGQILQATTQTNAAGQQQTIVTTDAAKHDQ 199
             .|:    |.|||:..  ..|..|:||.           ..:::..|..|:..:...|.||....
Mosquito   130 -KMV----DVDQLMRD--RDPATTLHAS-----------SSSSSNNNYTGKGSSSTATGAAAGSS 176

  Fly   200 AVIQAFLPARKRKPRVKKMSPTAPKISKVEGMDTIMGTPTSSHGSGSVQQVLGENGAEGQLLSST 264
            ....|...|.....|  .:.||:...|..         |...|.|..|... ..|.:..|..||:
Mosquito   177 TAGAAAATATSSSWR--DVPPTSSSGSHY---------PHYQHQSSPVIST-STNVSLAQSSSSS 229

  Fly   265 P-----------------IIKSEGQKVE------------TIVTMDPNNMIPVTSANAATGEIT- 299
            |                 .::.:.::.|            ...|..|.:....|||.::...::
Mosquito   230 PPYSYKSPYSSLYSRSPGAVERDREREERSRDRSASFSHAPATTSPPPHRTQSTSAGSSASSVSA 294

  Fly   300 --PAQGATGSSGGNTSGVLSTPKAKRAKHPPGTEKPRSRSQSEQPATCPICYAV------IRQSR 356
              ..|..|.||...:|.         |.|..|:.   :.|.|.||:|.....|:      :.|::
Mosquito   295 QIALQSQTASSNHQSSS---------ASHQSGSS---ASSASAQPSTVAAAAALAAGWPSLGQTQ 347

  Fly   357 NLRRHLELRHFAKPGVK--KEKKSKSGNDTTLDSSMEMNTTAEGDNTVGSDGAGGAGSAGG---- 415
             |...|...:.:...:.  |.||.:|.:....|:.:..|..|:. |...|..|||...||.
Mosquito   348 -LHSMLSSAYDSSTDMNPLKRKKLQSMSSMLRDTPILRNVLAQA-NPADSSQAGGVPGAGTAQAT 410

  Fly   416 ----QSSATSGKK------SSSGSSGSGSGALSSSGSVPQV------QTVQSLHTLQGVQVKKDP 464
                ||....|.|      ||..|:|||..::......|..      ..:.|.|...|
Mosquito   411 VATIQSQYQGGMKSDPDQPSSHHSNGSGYKSIKDQPHSPYADKSFDDDLLDSPHNFGG------- 468

  Fly   465 DA--------QQQQQQQQQQQQQQQQQAMTV---------------------------------- 487
            ||        |||:.:.::.:|..:...:..
Mosquito   469 DARLASYVPHQQQKPEWKRYKQYTRTDILNAIECVRKGMSALQASRKFGVPSRTLYDKVKKLGIT 533

  Fly   488 -------------------------------------SGATGGQVQQQVQQVQQQVQQQQQQQQQ 515
                                                 |||.||..........||:..|..|:
Mosquito   534 TGRPINRALKRSPSSGGSPASFPYGLSGASHMFGGPGSGAPGGPGGHPGGDHHQQLPSQSSQE-- 596

  Fly   516 QQQQLQHHQIIDSSGNITTATTSAQAAAAAQQQAAGQQQQLVAQSDGSESGAPLSI--------- 571
                       |.:.....|..:|.|||.|....||   :::....||..|.|.:|
Mosquito   597 -----------DDAAAAAAAAAAAAAAAMAHHHEAG---RMIKLEHGSHHGLPPTIPHPAAALLD 647

  Fly   572 ----AQVQTLQGHQIIGN---------------LNQVN--------------------ITDFQQQ 597
                .|....:|..|.|.               :|.::                    :......
Mosquito   648 PSFLQQALEARGGDIAGREALHAMAFAAAAHAAVNGMSTSPGTHGTARSPSPSVLMKYMRSVSMS 712

  Fly   598 QPQQQQQQQQQQQQQQQQQQQTQQ 621
            .|:..:....|||||::.:...::
Mosquito   713 SPEDDRHHSAQQQQQREARDLAER 736

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Trl	NP_001261846.1	BTB_POZ_BAB-like	33..116	CDD:349624	31/83 (37%)
		GAGA	319..372	CDD:462719	12/58 (21%)
rib	XP_061513904.1	None