Protein Alignment Tsen34 and TSEN34

DIOPT Version :10

• Sequence 1: NP_001036605.2
• Gene: Tsen34 / 2768977
• FlyBaseID: FBgn0053260
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_001269262.2
• Gene: TSEN34 / 79042
• HGNCID: 15506
• Length: 312
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 81/328 - (24%)
• Similarity: 131/328 - (39%)
• Gaps: 72/328 - (21%)

  Fly     1 MYLTLLNGTGFVFNVDDYMELRSKHRIMGAPVGTANTKGWSPNQST---LPVELSKFETQLLLDE 62
            :.:.:.||...|:..:....||.:..:.|..|| |..:|  |.|::   ||:.|...|.:||.:.
Human     2 LVVEVANGRSLVWGAEAVQALRERLGVGGRTVG-ALPRG--PRQNSRLGLPLLLMPEEARLLAEI 63

  Fly    63 NIAKLVDKSK-DLKAKPTAEKLEECKADFESRLLGQEEALKTEKLRETER--YMDKILTGK--RK 122
            ....||...: |.:....|  |...|...|...  ||::....:.|||.|  .::||..|:  :|
Human    64 GAVTLVSAPRPDSRHHSLA--LTSFKRQQEESF--QEQSALAAEARETRRQELLEKITEGQAAKK 124

  Fly   123 KLLKQ---------------------------GKNELA-------------AALTDKDVLLEMSV 147
            :.|:|                           |:.|.|             |.|....:|::::
Human   125 QKLEQASGASSSQEAGSSQAAKEDETSDGQASGEQEEAGPSSSQAGPSNGVAPLPRSALLVQLA- 188

  Fly   148 NFKFDRQNALLEVHCEHPTDHSAQIVTGPIVH----TNSLKYRVFKDLWRRGKYVTSGDAFGADF 208
                   .|........|.|...|....|  |    .:.|:|.:::|||.||.::::...||.||
Human   189 -------TARPRPVKARPLDWRVQSKDWP--HAGRPAHELRYSIYRDLWERGFFLSAAGKFGGDF 244

  Fly   209 LVYPGDPMIYHASHIVILHEQPVIKPL-ELIAKVRLSVIVNKSCVFAYEMEN--NEEEIHYQTVA 270
            |||||||:.:||.:|..........|| :|:|..||...|.|:.:......:  ..:|:....|.
Human   245 LVYPGDPLRFHAHYIAQCWAPEDTIPLQDLVAAGRLGTSVRKTLLLCSPQPDGFKSQEVSINLVY 309

  Fly   271 WCN 273
            .|:
Human   310 KCS 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsen34	NP_001036605.2	tRNA-intron_lyase_C	183..271	CDD:411767	31/90 (34%)
TSEN34	NP_001269262.2	tolA	<87..>169	CDD:236545	17/83 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	119..177		7/57 (12%)
		tRNA-intron_lyase_C	218..297	CDD:411767	29/78 (37%)