Protein Alignment CG32318 and KIF11

DIOPT Version :10

• Sequence 1: NP_995952.1
• Gene: CG32318 / 2768976
• FlyBaseID: FBgn0052318
• Length: 164
• Species: Drosophila melanogaster
• Sequence 2: NP_004514.2
• Gene: KIF11 / 3832
• HGNCID: 6388
• Length: 1056
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 63/342 - (18%)
• Similarity: 115/342 - (33%)
• Gaps: 121/342 - (35%)

  Fly    33 ISSARRLIALLRSVGD-----CQWLHHPPVIAEAIRRYDELWMPLISDLTVGLKPPMILPPLDVE 92
            ||||..:: ||.:.||     ||.||..|         ||       |:..|.:  ::|
Human    35 ISSALAMV-LLGAKGDTAVQICQALHLNP---------DE-------DVHQGFQ--LLL------ 74

  Fly    93 WVWFCHCLNPVSYSDYCERRFSKLIGK------PAIYDEENEDYAVLQCEKIWSLRYPLESFENR 151
                 |.||..:...||....::|..:      |...:         .|.|.:.......||...
Human    75 -----HNLNKQNNQKYCLTMANRLFVENTCELLPTFKE---------SCLKFYHSEMEQLSFAEA 125

  Fly   152 ADPDSLETVSL-----VNEDIKSLVKKQMFLWEKFSAPYMSETVYLIAARLRYKGFLLILHKFKD 211
            |: :|.:.:::     .|..|..|:.|.         ...|:|..::|..|.:.|
Human   126 AE-ESRQHINMWVSKQTNGKIPDLLSKD---------SVNSQTRLILANALYFHG---------- 170

  Fly   212 EVSSLIPASDILLMWLTHQSYPTVYKDDVDEMLEEMTRKVVQVGEKVEKTEVETTKELW--DRYF 274
                         .|.              :..|:...|  ::..|:.|.|....:.:|  |..|
Human   171 -------------TWC--------------KRFEKNRTK--EMPFKINKKETRPVQMMWREDTLF 206

  Fly   275 NQPYEKAGGELSIIANESGLSNNTMFYWP-----VSDMDVNTAYKSI----RPRFV--LELCIFL 328
            :...::...::.::..| |:..|.:...|     :|.::.|..::.:    :|.|:  .|..::.
Human   207 HAYVKEIQAQVLVMPYE-GIDLNFVVLLPDEGVDISKVENNLTFEKLTAWTKPEFMNRTEFHVYY 270

  Fly   329 RLNPKAEQNESIDRSFL 345
               ||.:..|..|.:.|
Human   271 ---PKFQLQEDYDMNSL 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32318	NP_995952.1	Motor_domain	17..>106	CDD:473979	21/77 (27%)
		GINS_B_Psf1	115..163	CDD:412032	8/58 (14%)
KIF11	NP_004514.2	KISc_BimC_Eg5	16..368	CDD:276815	63/342 (18%)
		PRK12704	350..>508	CDD:237177
		YhaN	380..>761	CDD:443752
		Microtub_bind	916..1053	CDD:464048