Protein Alignment ind and En1

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_001385634.1
• Gene: En1 / 685360
• RGDID: 1595088
• Length: 409
• Species: Rattus norvegicus
• Alignment Length: 324
• Identity: 96/324 - (29%)
• Similarity: 124/324 - (38%)
• Gaps: 106/324 - (32%)

  Fly     4 SFLMDSLLSDRPNLSQKKEKL-------------GSPGG--------SPTAAA----------AV 37
            :|.:|::|  ||:...|||:.             |:.||        |.|.|.          |.
  Rat   117 NFFIDNIL--RPDFGCKKEQPLPQLLVASAAAGGGAAGGGSRVERDRSQTGAGRDPVHSLGTRAS 179

  Fly    38 AAAAML--PSIPMLP----YPASYVGSYLFSLGIQQQQQQQQQQQQHAAAAAAAAAAAAALQQHP 96
            .||::|  |.....|    .||:.||:     |..:...........|||||||.|||||....|
  Rat   180 GAASLLCAPDANCGPPDGSQPATAVGA-----GASKAGNPAAAAAAAAAAAAAAVAAAAAAASKP 239

  Fly    97 HVS--SSPGSLYHPYAQLFASKRKSSGFSNYEGCYPSPPLSANPNSQQLPPIHNLYGSPVV---G 156
            ..|  .|.||...|.||       .:.|..:.   |:..|..:.|           |.|||   .
  Rat   240 SDSGGGSGGSAGSPGAQ-------GAKFPEHN---PAILLMGSAN-----------GGPVVKTDS 283

  Fly   157 GLPLPEPG-SFCTSPSASSSASLDYTNNFDEPQGKRFKHESSCSPNSSPLKNHSSGGPVEITPLI 220
            ..||..|. .:||                      |:....|..|.:..||...
  Rat   284 QQPLVWPAWVYCT----------------------RYSDRPSSGPRTRKLKKKK----------- 315

  Fly   221 NDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKK 284
            |:..|  ||.|||||:.||..|:.||..|.|::..||..:|..|.|:|.|:||||||:|.|.||
  Rat   316 NEKED--KRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKK 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	29/55 (53%)
En1	NP_001385634.1	Homeodomain	322..377	CDD:459649	28/54 (52%)
		Engrail_1_C_sig	378..408	CDD:431338	96/324 (30%)