DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ind and hoxb3

DIOPT Version :9

Sequence 1:	NP_996087.2	Gene:	ind / 2768974	FlyBaseID:	FBgn0025776	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001015971.1	Gene:	hoxb3 / 548725	XenbaseID:	XB-GENE-482576	Length:	386	Species:	Xenopus tropicalis

Alignment Length:	248	Identity:	80/248 - (32%)
Similarity:	109/248 - (43%)	Gaps:	67/248 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 YHPYAQLFASKRKSSGFSNYEGCYPSPPLSANPNSQ---------------QLPPIHNLYGSPVV 155
            |:....||......:|...|||...|.|.|::.:::               .|....||.||
Frog     6 YYDNPTLFGGYPYQAGSLGYEGPQQSFPTSSHMDNEFQRSSCSLQSLGHSGPLVKAKNLNGS--- 67

  Fly   156 GGLPLPEPGSFCTSPSASSSAS--LDYTNNFDEPQGKRFKHESSCS-PNSSPLKNHSSGGPV--E 215
                       |..|:.||..|  |..|.|   |........|..| ...||.|:.:||.|.  :
Frog    68 -----------CMRPNLSSEQSQPLSPTAN---PSSNTNSSSSQASLSKPSPAKSQASGSPASKQ 118

  Fly   216 ITPLINDY--------------------------ADSSKRIRTAFTSTQLLELEREFSHNAYLSR 254
            |.|.:.:.                          :.:|||.|||:||.||:|||:||..|.||.|
Frog   119 IFPWMKESRQNSKQKSSPPAPAAESCGGDRSPPGSSASKRARTAYTSAQLVELEKEFHFNRYLCR 183

  Fly   255 LRRIEIANRLRLSEKQVKIWFQNRRVKQKKGGSESPTFNLSTNSNG-SPQASP 306
            .||:|:||.|.|||:|:||||||||:|.||   :.....:|::|.| ||.::|
Frog   184 PRRVEMANLLNLSERQIKIWFQNRRMKYKK---DQKVKGMSSSSGGASPTSTP 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeobox	231..283	CDD:278475	35/51 (69%)
hoxb3	NP_001015971.1	Homeobox	160..212	CDD:306543	35/51 (69%)
hoxb3	NP_001015971.1	DUF4074	325..384	CDD:315871
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	94	1.000	Inparanoid score	I4928
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.960