Protein Alignment ind and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: XP_038962557.1
• Gene: Nkx2-4 / 366213
• RGDID: 1304985
• Length: 353
• Species: Rattus norvegicus
• Alignment Length: 324
• Identity: 89/324 - (27%)
• Similarity: 122/324 - (37%)
• Gaps: 84/324 - (25%)

  Fly     5 FLMDSLLSDRPNLSQKKEKLGS------PG-GSPTAAAAVAAAAMLPSIPMLPYPASYVGSYLFS 62
            |.:..:||.   :.:..:|.|.      || |:|..|||..|....||     ..|:.|.
  Rat    11 FSVSDILSP---IEETYKKFGGVMDGAPPGLGAPLGAAAYRAPPTGPS-----SQAAAVA----- 62

  Fly    63 LGIQQQQQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHPYAQLFASKRKSSGFSNYEG 127
             |:|............|||||||||||||....|     ||....|::.:              |
  Rat    63 -GMQPPHAMAGHNAAAAAAAAAAAAAAAATYHMP-----PGVSQFPHSAM--------------G 107

  Fly   128 CYPSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFDEPQGKRF 192
            .|.:..|.   |..:||    .|...:.||              |:::|:..|..|.|    .|:
  Rat   108 SYCNGGLG---NMGELP----AYTDGMRGG--------------AAAAATGWYGANTD----PRY 147

  Fly   193 KHESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRI------------RTAFTSTQLLELERE 245
               ||.|....|....:..|...:|.:    ||::|.:            |..|:..|:.||||.
  Rat   148 ---SSISRFMGPSAGVNVAGMGSLTGI----ADAAKSLAPLHAAAPRRKRRVLFSQAQVYELERR 205

  Fly   246 FSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKKGGSESPTFNLSTNSNGSPQASPVSP 309
            |....|||...|..:|:.:.|:..||||||||.|.|.|:...:.....|.......|...|..|
  Rat   206 FKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGGLGPPPPPPPP 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	25/67 (37%)
Nkx2-4	XP_038962557.1	Homeodomain	188..244	CDD:459649	24/55 (44%)