Protein Alignment ind and HOXD11

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_067015.2
• Gene: HOXD11 / 3237
• HGNCID: 5134
• Length: 338
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 85/306 - (27%)
• Similarity: 117/306 - (38%)
• Gaps: 119/306 - (38%)

  Fly    25 GSPGGSPTAAAAVAAAAMLPSIPMLPYPASYVGSYLFSLGIQQQQQQQQQQQQHAAAAAAAAAAA 89
            |.|||....|...|           ||.|:                        |||||||||||
Human    91 GGPGGGGGGAGGYA-----------PYYAA------------------------AAAAAAAAAAA 120

  Fly    90 --AALQQH---------------PH-VSSSPGSLYHP-------YAQLFASKRKSSGFSNYEGCY 129
              ||:|:.               |. |.::||..:.|       |:.:..:.....||..:....
Human   121 EEAAMQRELLPPAGRRPDVLFKAPEPVCAAPGPPHGPAGAASNFYSAVGRNGILPQGFDQFYEAA 185

  Fly   130 PSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPE---------------PGSFCTSPSASSSASLD 179
            |.||. |.|  |..||     .:|     |.||               .||.||..:..|
Human   186 PGPPF-AGP--QPPPP-----PAP-----PQPEGAADKGDPRTGAGGGGGSPCTKATPGS----- 232

  Fly   180 YTNNFDEPQGKRFKHESSCSPNSSP------LKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQ 238
                  ||:|..   |.|......|      .|:.|:..|           ..|::.|..:|..|
Human   233 ------EPKGAA---EGSGGDGEGPPGEAGAEKSSSAVAP-----------QRSRKKRCPYTKYQ 277

  Fly   239 LLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKK 284
            :.||||||..|.|:::.:|::::..|.|:::||||||||||:|:||
Human   278 IRELEREFFFNVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	25/55 (45%)
HOXD11	NP_067015.2	DUF3528	26..185	CDD:432284	31/128 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	179..270		27/128 (21%)
		Homeodomain	267..323	CDD:459649	25/55 (45%)