Protein Alignment ind and HOXB3

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: XP_016880049.1
• Gene: HOXB3 / 3213
• HGNCID: 5114
• Length: 578
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 96/349 - (27%)
• Similarity: 132/349 - (37%)
• Gaps: 123/349 - (35%)

  Fly    12 SDRPNLSQKKEKLGSP---GGSPTAAAAVAAAAMLPSIPMLPYPASYVGSYLFSLGIQQQQQQQQ 73
            :.||...:.....|.|   |....||.:.|....:..:|:||...:...::|            :
Human   139 TQRPAARRCPRPSGRPHRRGDLSPAARSGARCEYILCLPVLPSSVAKAATHL------------E 191

  Fly    74 QQQQHAAAAAAAAAAAAALQQHPHVSSSP--GSLYHPYAQLFASKRKSSGFSNYEGCYPSPPLSA 136
            ...|.:|.:..:...||     ||..|..  ||...|                  |..|. ||||
Human   192 GDYQRSACSLQSLGNAA-----PHAKSKELNGSCMRP------------------GLAPE-PLSA 232

  Fly   137 NPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFDEPQGKRFKHESSCSP- 200
            .|.|   ||                        |||:.:::   |:|.....|........|.|
Human   233 PPGS---PP------------------------PSAAPTSA---TSNSSNGGGPSKSGPPKCGPG 267

  Fly   201 -----------------NSSPLKNHS---------------------------SGGPVEITPLIN 221
                             .:|.|||:|                           .||..:.:|
Human   268 TNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGGGGGGGGGGDKSP--- 329

  Fly   222 DYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKKGG 286
            ..:.:|||.|||:||.||:|||:||..|.||.|.||:|:||.|.|||:|:||||||||:|.||
Human   330 PGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKK-- 392

  Fly   287 SESPTFNLSTNSNG-SPQASPVSP 309
             :.....|:::|.| ||..||..|
Human   393 -DQKAKGLASSSGGPSPAGSPPQP 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	37/55 (67%)
HOXB3	XP_016880049.1	Homeodomain	336..392	CDD:459649	37/55 (67%)
		DUF4074	513..576	CDD:463833