Protein Alignment ind and HOXA11

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_005514.1
• Gene: HOXA11 / 3207
• HGNCID: 5101
• Length: 313
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 74/300 - (24%)
• Similarity: 122/300 - (40%)
• Gaps: 89/300 - (29%)

  Fly    43 LPSIPMLPY-PASYVGSYLFSLGIQQQQQQQQ----------QQQQHAAAAAAAAAAAAAL---- 92
            |||  .||. |:|...:|.:|..:.|.|..::          ..:.|.....|...:|..|
Human    30 LPS--FLPQTPSSRPMTYSYSSNLPQVQPVREVTFREYAIEPATKWHPRGNLAHCYSAEELVHRD 92

  Fly    93 -QQHPHVSSSPG--------SLYHPYAQLFASKRKSSGFSNYEGCYPSPPLSAN-----PNSQQL 143
             .|.|..:..||        ::||                     :|:|.:|:|     ..:..|
Human    93 CLQAPSAAGVPGDVLAKSSANVYH---------------------HPTPAVSSNFYSTVGRNGVL 136

  Fly   144 PP-----IHNLYGSPV-VGGLPLP--------EPGSFCTSPSASSSAS-LDYTNNFD-------- 185
            |.     ....||:|. :.....|        .|.:..||.:|:::|: ...|::.|
Human   137 PQAFDQFFETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCR 201

  Fly   186 ------EPQGKRFKHESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELER 244
                  |.:.:|.:.|||.||.||........|        ......:::.|..:|..|:.||||
Human   202 ETAAAAEEKERRRRPESSSSPESSSGHTEDKAG--------GSSGQRTRKKRCPYTKYQIRELER 258

  Fly   245 EFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKK 284
            ||..:.|:::.:|::::..|.|:::||||||||||:|:||
Human   259 EFFFSVYINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKK 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	24/55 (44%)
HOXA11	NP_005514.1	DUF3528	25..153	CDD:432284	30/145 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..246		18/99 (18%)
		Homeodomain	242..298	CDD:459649	24/55 (44%)