Protein Alignment ind and HOXA1

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_005513.2
• Gene: HOXA1 / 3198
• HGNCID: 5099
• Length: 335
• Species: Homo sapiens
• Alignment Length: 290
• Identity: 79/290 - (27%)
• Similarity: 109/290 - (37%)
• Gaps: 94/290 - (32%)

  Fly    50 PYPASY------------------VGSYLFS-----LGIQQQQQQQQQQQQHAAAAAAAAAAAAA 91
            |.||:|                  .||..||     ..:.|:........|.|.|..:...::..
Human    75 PQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSGGYPQCAPAVYSGNLSSPM 139

  Fly    92 LQQHPH-------VSSSPGSLYHPYAQLFASKRKSSGFSNYEGCYPSPPLSANPNSQQLPPIHNL 149
            :|.|.|       ...||..::|.|.|    :.:|...:.|              :..|.|:|..
Human   140 VQHHHHHQGYAGGAVGSPQYIHHSYGQ----EHQSLALATY--------------NNSLSPLHAS 186

  Fly   150 YGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFDEPQGKRFKHESSCSPNSSPLKNHSSGGPV 214
            :...             |.||::.:|:.   ...||..:.||           :|.|....|.
Human   187 HQEA-------------CRSPASETSSP---AQTFDWMKVKR-----------NPPKTGKVGE-- 222

  Fly   215 EITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRR 279
                  ..|......:||.||:.||.|||:||..|.||:|.||:|||..|:|:|.||||||||||
Human   223 ------YGYLGQPNAVRTNFTTKQLTELEKEFHFNKYLTRARRVEIAASLQLNETQVKIWFQNRR 281

  Fly   280 VKQKKGGSESPTFNLSTNSNGSPQASPVSP 309
            :||||...|           |....||.:|
Human   282 MKQKKREKE-----------GLLPISPATP 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	35/55 (64%)
HOXA1	NP_005513.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..80		3/4 (75%)
		Interaction with OGT. /evidence=ECO:0000250|UniProtKB:P09022	75..203		29/161 (18%)
		COG5576	176..>286	CDD:227863	51/158 (32%)
		Antp-type hexapeptide	204..209		2/4 (50%)
		Homeodomain	233..286	CDD:459649	35/52 (67%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..335		10/31 (32%)