Protein Alignment ind and HMX2

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_005510.1
• Gene: HMX2 / 3167
• HGNCID: 5018
• Length: 273
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 70/282 - (24%)
• Similarity: 99/282 - (35%)
• Gaps: 95/282 - (33%)

  Fly     4 SFLMDSLLSDRPNLSQKKEKLGSPGGSPTAAAAVAAAAMLPSIPMLPYPASYVGSYLFSLGIQQQ 68
            ||.:.|:|                ||.|:.|         |..| :.:||.     ..||.:..:
Human    19 SFTIQSIL----------------GGGPSEA---------PREP-VGWPAR-----KRSLSVSSE 52

  Fly    69 QQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHPYAQLFASKRKSSGFSNYEGCYPSP- 132
            :::.....:          |.|......|.....|..:||                     |.|
Human    53 EEEPDDGWK----------APACFCPDQHGPKEQGPKHHP---------------------PIPF 86

  Fly   133 PLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFDEPQGKRFKHESS 197
            |....|.           ||   ||   ..||....:|..|.|.|     :|.| :.:|.....|
Human    87 PCLGTPK-----------GS---GG---SGPGGLERTPFLSPSHS-----DFKE-EKERLLPAGS 128

  Fly   198 CSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIAN 262
            .||.|...::    |..|     .....:.|:.||.|:.:|:.:||..|....|||...|..:|:
Human   129 PSPGSERPRD----GGAE-----RQAGAAKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLAS 184

  Fly   263 RLRLSEKQVKIWFQNRRVKQKK 284
            .|:|:|.|||.||||||.|.|:
Human   185 SLQLTETQVKTWFQNRRNKWKR 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	26/55 (47%)
HMX2	NP_005510.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		44/226 (19%)
		Homeodomain	150..206	CDD:459649	26/55 (47%)