Protein Alignment ind and HLX

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_068777.1
• Gene: HLX / 3142
• HGNCID: 4978
• Length: 488
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 90/349 - (25%)
• Similarity: 125/349 - (35%)
• Gaps: 112/349 - (32%)

  Fly    24 LGSPGGSPTAAAAVAAAAM---LPSI------------PMLPYP-------------------AS 54
            :|..|.:|...|..:|||:   |.|:            |:.|.|                   |:
Human    54 VGDLGAAPEGLAGASAAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAA 118

  Fly    55 YVGSYLFSLGIQQQQQQQQQQQQH-----AAAAAAAAAAAAALQQHPHVSSSPGSLYHPYAQLFA 114
            |...:     .||||||||.|||.     .|.|....|:...:..:||.|.|        |...:
Human   119 YHHHH-----PQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPHHSGS--------APAPS 170

  Fly   115 SKRKSSGFSNYEGCYPSPPLSA--NPNSQQLPPIHNLYGSPVVGGLPL--------PEPGSFCTS 169
            ||....|....        |||  :|..::...:.:| .|.:.||.|.        |..|.|..|
Human   171 SKDLKFGIDRI--------LSAEFDPKVKEGNTLRDL-TSLLTGGRPAGVHLSGLQPSAGQFFAS 226

  Fly   170 --PSASSSASLDYTNNFDEPQGKRFKHESSCSPNSSPLKNHSSGGPVEITPLIND-----YADSS 227
              |...:||.|...|:               :|.:|.........|.....|..|     |....
Human   227 LDPINEASAILSPLNS---------------NPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKR 276

  Fly   228 KRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVK---------QK 283
            ...|..|::.|...||:.|....|:::..|.::|..|.|::.|||:||||||:|         ||
Human   277 SWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQK 341

  Fly   284 ---KGGSESPTFNLSTNSNGSPQA 304
               |...|.|       |.|:|.|
Human   342 DKDKEAGEKP-------SGGAPAA 358

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	23/67 (34%)
HLX	NP_068777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..173		21/67 (31%)
		Homeodomain	273..333	CDD:459649	21/59 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..488		9/35 (26%)