DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ind and hoxd3a

DIOPT Version :9

Sequence 1:	NP_996087.2	Gene:	ind / 2768974	FlyBaseID:	FBgn0025776	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_571200.1	Gene:	hoxd3a / 30349	ZFINID:	ZDB-GENE-990415-120	Length:	396	Species:	Danio rerio

Alignment Length:	243	Identity:	79/243 - (32%)
Similarity:	102/243 - (41%)	Gaps:	72/243 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 YHPYAQLFASKRKSSGFSNYEGCYPSP--PLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCT 168
            |.|..|.|:|       |:.|..|.||  |:......|......::.||              |.
Zfish    26 YGPTHQGFSS-------SSIENDYQSPICPIQTTSVRQATHKNGDINGS--------------CM 69

  Fly   169 SPSASSSASLDYTNNFDEPQGKRFKHESSCSPNSSPL---KNHSSGGPVEITPLINDY------- 223
            .||||...|  ...:..|.|.......||.||:::..   |:.||.|....||:|:..
Zfish    70 RPSASQGNS--QPESISEQQQAAPLAASSPSPSTNSTQKKKSPSSNGSSTATPVISKQIFPWMKE 132

  Fly   224 -------------------------ADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANR 263
                                     ..:|||:|||:||.||:|||:||..|.||.|.||:|:||.
Zfish   133 TRQNAKQKSTNCPAAGETCDDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANL 197

  Fly   264 LRLSEKQVKIWFQNRRVKQK-----KGGSESPTFNLSTNSNGSPQASP 306
            |.|:|:|:||||||||:|.|     ||...||.       ..||..||
Zfish   198 LNLTERQIKIWFQNRRMKYKKDQKSKGIMHSPL-------GHSPDRSP 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeobox	231..283	CDD:278475	34/51 (67%)
hoxd3a	NP_571200.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	18..163		34/159 (21%)
		Abdominal-A	116..237	CDD:332641	47/127 (37%)
		Antp-type hexapeptide	126..131		0/4 (0%)
		Homeobox	165..217	CDD:306543	34/51 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	219..246		8/27 (30%)
		DUF4074	333..394	CDD:315871
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	364..396
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810