Protein Alignment ind and en2a

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_571119.2
• Gene: en2a / 30243
• ZFINID: ZDB-GENE-980526-167
• Length: 265
• Species: Danio rerio
• Alignment Length: 278
• Identity: 73/278 - (26%)
• Similarity: 106/278 - (38%)
• Gaps: 65/278 - (23%)

  Fly    65 IQQQQQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHPY--AQLFA--------SKRKS 119
            :.:.:|..:..:|..|:..:.:|....||       :||:|..|:  ...|.        .::|.
Zfish     1 MDENEQSARDVEQRGASDESNSAIRPLLQ-------APGNLQLPHRITNFFIDNILRPDFGRKKE 58

  Fly   120 SGFSNYEGCYPSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNF 184
            :..:.||..:     .|..|.....|.....||.|    |..|..:..|| |....|.::    .
Zfish    59 ANITRYEDNH-----GARENHNPTGPSTGQVGSTV----PAEEASTTHTS-SGGKEAEIE----S 109

  Fly   185 DEPQGKRFKHESSC--SPNSSPLKNHS----------------------SGGPVEITPLINDYAD 225
            :||...|.::...|  |.:.|...|.:                      |.||....|.....:.
Zfish   110 EEPLKPRGENVDQCLGSESDSSQSNSNGQTGQGMLWPAWVYCTRYSDRPSSGPRSRKPKKKAASK 174

  Fly   226 SSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKKGGS--- 287
            ..||.|||||:.||..|:.||..|.||:..||..:|..|.|:|.|:||||||:|.|.||...
Zfish   175 EDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELGLNESQIKIWFQNKRAKIKKASGVKN 239

  Fly   288 -------ESPTFNLSTNS 298
                   ....:|.||.|
Zfish   240 GLAIHLMAQGLYNHSTTS 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	30/55 (55%)
en2a	NP_571119.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..30		6/35 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..142		20/90 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	155..180		6/24 (25%)
		Homeodomain	177..233	CDD:459649	30/55 (55%)
		Engrail_1_C_sig	234..264	CDD:431338	4/24 (17%)