Protein Alignment ind and TLX3

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_066305.2
• Gene: TLX3 / 30012
• HGNCID: 13532
• Length: 291
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 69/254 - (27%)
• Similarity: 101/254 - (39%)
• Gaps: 39/254 - (15%)

  Fly    44 PSIPMLPYPASYVGSYLFSLGIQQQQQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHP 108
            |:....|:|...:     |.||.|......|.   :|.|......|:.|...|  ...||:.|..
Human     4 PASAQTPHPHEPI-----SFGIDQILNSPDQD---SAPAPRGPDGASYLGGPP--GGRPGATYPS 58

  Fly   109 YAQLFASKRKSSGFSNYEGCYPSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSAS 173
            ....||.  ..:.|.: .|.| |..||..|......|.|.    |:.|.:|.|.|.:....||..
Human    59 LPASFAG--LGAPFED-AGSY-SVNLSLAPAGVIRVPAHR----PLPGAVPPPLPSALPAMPSVP 115

  Fly   174 SSASLDYTNNFDEPQGKRFKHESSCSPNSSPLKNHSSGG----PVEIT-----PLINDYADSSKR 229
            :.:||...|.......:||            :|:..:..    |..:|     |..|......|:
Human   116 TVSSLGGLNFPWMESSRRF------------VKDRFTAAAALTPFTVTRRIGHPYQNRTPPKRKK 168

  Fly   230 IRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKKGGSE 288
            .||:|:..|:.|||:.|....||:...|..:|..|::::.|||.||||||.|.::..:|
Human   169 PRTSFSRVQICELEKRFHRQKYLASAERAALAKSLKMTDAQVKTWFQNRRTKWRRQTAE 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	24/55 (44%)
TLX3	NP_066305.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		15/61 (25%)
		Homeodomain	167..223	CDD:459649	24/55 (44%)