DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ind and Meox2

DIOPT Version :9

Sequence 1:	NP_996087.2	Gene:	ind / 2768974	FlyBaseID:	FBgn0025776	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_058845.2	Gene:	Meox2 / 29279	RGDID:	3079	Length:	303	Species:	Rattus norvegicus

Alignment Length:	277	Identity:	82/277 - (29%)
Similarity:	111/277 - (40%)	Gaps:	94/277 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 QHAAAAAAAAAAAAALQQHPHVSSSPG----SLYHPYAQLFASKRKS--SGFSNYEGCYPS---- 131
            :|.......:..|.|...||...||..    |.:..|.:|..|....  :|:.|.||.:.|
  Rat     2 EHPLFGCLRSPHATAQGLHPFSQSSLALHGRSDHMSYPELSTSSSSCIIAGYPNEEGMFASQHHR 66

  Fly   132 ---------------------------PPLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGS---- 165
                                       |.:|:.|::.:    |:|...|..|| | ||.||
  Rat    67 GHHHHHHHHHHHHQQQQHQALQSNWHLPQMSSPPSAAR----HSLCLQPDSGG-P-PELGSSPPV 125

  Fly   166 FC--------TSPSASSSASLDYTNNFDEP------QGKRFKHESSCSP--------NSSPLKNH 208
            .|        ::|:.::.|..||......|      .|.:.|.:||.|.        ||.|.|.
  Rat   126 LCSNSSSLGSSTPTGAACAPGDYGRQALSPAEVEKRSGSKRKSDSSDSQEGNYKSEVNSKPRKE- 189

  Fly   209 SSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKI 273
                                  |||||..|:.|||.||:|:.||:||||.|||..|.|:|:|||:
  Rat   190 ----------------------RTAFTKEQIRELEAEFAHHNYLTRLRRYEIAVNLDLTERQVKV 232

  Fly   274 WFQNRRVKQK--KGGSE 288
            ||||||:|.|  |||.:
  Rat   233 WFQNRRMKWKRVKGGQQ 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeobox	231..283	CDD:278475	34/51 (67%)
Meox2	NP_058845.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	63..191		28/156 (18%)
		Homeobox	190..243	CDD:395001	34/52 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	279..303
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810