DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ind and Hoxd4

DIOPT Version :9

Sequence 1:	NP_996087.2	Gene:	ind / 2768974	FlyBaseID:	FBgn0025776	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_001099355.1	Gene:	Hoxd4 / 288153	RGDID:	1309690	Length:	251	Species:	Rattus norvegicus

Alignment Length:	254	Identity:	82/254 - (32%)
Similarity:	103/254 - (40%)	Gaps:	78/254 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 GSLYHPYAQLFASKRKSSGFSNYEGCYPSP-------------PLSA-----------NPNSQQL 143
            |.|....|..:.|..:.|.|.. .|.||.|             |.||           .|.|...
  Rat    27 GYLGEQGADYYGSGAQGSDFQP-PGLYPRPDFGEQPFGGGGPGPGSALPARGHGQEPSGPGSHYS 90

  Fly   144 PPIHNLYGSPVVGGLPLPEPGS-FCTSPSASSSASLDYTNNFDEPQGKRFK------------HE 195
            .|     |.|.....|.|.||: .|:.|          |.....|.|...|            |.
  Rat    91 AP-----GEPCPAPPPAPLPGARACSQP----------TGPKQPPPGTALKQPAVVYPWMKKVHV 140

  Fly   196 SSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEI 260
            :|.:|      |::.|.|              ||.|||:|..|:||||:||..|.||:|.|||||
  Rat   141 NSVNP------NYTGGEP--------------KRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEI 185

  Fly   261 ANRLRLSEKQVKIWFQNRRVKQKKGGSESPTFNLSTNSNG--SPQASP---VSPQVKVH 314
            |:.|.|||:|:||||||||:|.||......|...|::|:.  |..|:|   :.|..|.|
  Rat   186 AHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSCSSSAAPSQHLQPMAKDH 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeobox	231..283	CDD:278475	35/51 (69%)
Hoxd4	NP_001099355.1	Homeobox	155..209	CDD:395001	35/53 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810