Protein Alignment ind and GSX1

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_663632.1
• Gene: GSX1 / 219409
• HGNCID: 20374
• Length: 264
• Species: Homo sapiens
• Alignment Length: 354
• Identity: 108/354 - (30%)
• Similarity: 127/354 - (35%)
• Gaps: 171/354 - (48%)

  Fly     1 MSRSFLMDSLLSDRPNLSQKKEKLGSP---------------GGSPTAAAAVAAAAML------- 43
            |.||||:|||:  .....:||...|||               |.||.|..|..|..:.
Human     1 MPRSFLVDSLV--LREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVT 63

  Fly    44 ----------PSIPML-----PYPASYVGSYLFSLGIQQQQQQQQQQQQHAAAA------AAAAA 87
                      |::|:|     |:.:.|..:   .||           :||:|.:      .||||
Human    64 ASQLHGPPGPPALPLLKASFPPFGSQYCHA---PLG-----------RQHSAVSPGVAHGPAAAA 114

  Fly    88 AAAALQQHPHVSSSPGSLYHPYAQLFASKRKSSGFSNYEGCYPSPPLSANPNSQQLPPIHNLYGS 152
            |||||                                |:..|
Human   115 AAAAL--------------------------------YQTSY----------------------- 124

  Fly   153 PVVGGLPLPEPGSF-CTSPSASSSASLDYTNNFDEPQGKRFKHESSCSPNSSPLKNHSSGGPVEI 216
                  |||:|..| |.|..:||                          |..|
Human   125 ------PLPDPRQFHCISVDSSS--------------------------NQLP------------ 145

  Fly   217 TPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVK 281
                     ||||:||||||||||||||||:.|.|||||||||||..|.||||||||||||||||
Human   146 ---------SSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVK 201

  Fly   282 QKKGGSESPTFNLSTNSNGSPQASPVSPQ 310
            .||.|..|   |......|.......:||
Human   202 HKKEGKGS---NHRGGGGGGAGGGGSAPQ 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	47/55 (85%)
GSX1	NP_663632.1	SNAG domain. /evidence=ECO:0000250	1..20		9/20 (45%)
		Homeodomain	148..204	CDD:459649	47/55 (85%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	201..264		9/30 (30%)