Protein Alignment ind and EMX1

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 86/316 - (27%)
• Similarity: 118/316 - (37%)
• Gaps: 121/316 - (38%)

  Fly     3 RSFLMDSLLSDRPNLSQKKEKLGSPG--------GSPTAAAAVAAAAMLPSIPMLPYP----ASY 55
            |.|.::||::          |.|..|        ||...|||.:...:.|:....|:|    |::
Human    41 RGFTIESLVA----------KDGGTGGGTGGGGAGSHLLAAAASEEPLRPTALNYPHPSAAEAAF 95

  Fly    56 VGSYLFSLGIQQQQQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHPYAQLFASKRKSS 120
            |..:                     .|||||.|..:|...|.: ..|.::.||...:
Human    96 VSGF---------------------PAAAAAGAGRSLYGGPEL-VFPEAMNHPALTV-------- 130

  Fly   121 GFSNYEGCYPSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDY----- 180
                    :|:..|.|:|    |.|.|:.:|                    |.....|.:
Human   131 --------HPAHQLGASP----LQPPHSFFG--------------------AQHRDPLHFYPWVL 163

  Fly   181 TNNFDEPQGKRFKHESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELERE 245
            .|.|   .|.||  ::|..|....|.:    ||         :|...|||||||:.:|||.|||.
Human   164 RNRF---FGHRF--QASDVPQDGLLLH----GP---------FARKPKRIRTAFSPSQLLRLERA 210

  Fly   246 FSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVK--------------QKKGGS 287
            |..|.|:....|.::|..|.|||.|||:||||||.|              |||.||
Human   211 FEKNHYVVGAERKQLAGSLSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGS 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	33/69 (48%)
EMX1	NP_004088.2	Homeodomain	193..249	CDD:459649	32/55 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	249..290		5/18 (28%)