Protein Alignment ind and Nkx2-3

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_032725.1
• Gene: Nkx2-3 / 18089
• MGIID: 97348
• Length: 362
• Species: Mus musculus
• Alignment Length: 294
• Identity: 70/294 - (23%)
• Similarity: 107/294 - (36%)
• Gaps: 102/294 - (34%)

  Fly    48 MLPYPASYVGSYLFSLGIQQQQQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHPYAQL 112
            |||.|   |.|..||  ::.....:||:..|      .|...|.|:||.|  |:|..|
Mouse     2 MLPSP---VTSTPFS--VKDILNLEQQRHFH------GAHLQAELEQHFH--SAPCML------- 46

  Fly   113 FASKRKSSGFSNYEGCYPSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSAS 177
              :..:.:.||:           |....::                   |.|.           .
Mouse    47 --ATAEGTQFSD-----------AGEEDEE-------------------EEGE-----------K 68

  Fly   178 LDYTNNFDEPQGKRFKH-ESSCSPNS---SPLKNHSSGGPVEITPLINDYADSS----------- 227
            |.|.|:....:|    | :|...|.|   :.|::..||...:...::::.:..|
Mouse    69 LSYLNSLAAAEG----HGDSGLCPQSYVHTVLRDACSGPKEQEEEVVSERSQKSCQLKKSLEAAG 129

  Fly   228 ----------------KRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQ 276
                            ::.|..|:..|:.||||.|....|||...|..:|:.|:|:..|||||||
Mouse   130 DCKTSEDGERPKPRSRRKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQ 194

  Fly   277 NRRVKQKKGGSESPTFNLSTNSNGSPQ---ASPV 307
            |||.|.|: ..:..:..|.|::...|.   |.||
Mouse   195 NRRYKCKR-QRQDKSLELGTHAPPPPPRRVAVPV 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	26/55 (47%)
Nkx2-3	NP_032725.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..149		0/22 (0%)
		Homeodomain	146..202	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..222		3/18 (17%)