Protein Alignment ind and Nkx2-2

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_035049.1
• Gene: Nkx2-2 / 18088
• MGIID: 97347
• Length: 273
• Species: Mus musculus
• Alignment Length: 208
• Identity: 60/208 - (28%)
• Similarity: 81/208 - (38%)
• Gaps: 37/208 - (17%)

  Fly   126 EGCYPSPPLSANPNS-------QQLP---PIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDY 180
            ||  |.|...|.|..       |.||   |.::...:|....|...|...:.....|:|:...|.
Mouse    37 EG--PEPAKRAGPLGQGALDAVQSLPLKSPFYDSSDNPYTRWLASTEGLQYSLHGLAASAPPQDS 99

  Fly   181 TNNFDEPQGKRFKHESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELERE 245
            ::...||....       ||::.  |....||        .|.....|| |..|:..|..||||.
Mouse   100 SSKSPEPSADE-------SPDND--KETQGGG--------GDAGKKRKR-RVLFSKAQTYELERR 146

  Fly   246 FSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKKGGSESPTFNLSTNSNGSPQASPVSPQ 310
            |....|||...|..:|:.:||:..||||||||.|.|.|:..:|.   .:......||:...|...
Mouse   147 FRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYKMKRARAEK---GMEVTPLPSPRRVAVPVL 208

  Fly   311 VK----VHELKVE 319
            |:    .|.||.:
Mouse   209 VRDGKPCHALKAQ 221

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	27/55 (49%)
Nkx2-2	NP_035049.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		6/20 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..131		11/56 (20%)
		Homeodomain	129..185	CDD:459649	27/56 (48%)