Protein Alignment ind and DLX1

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_835221.2
• Gene: DLX1 / 1745
• HGNCID: 2914
• Length: 255
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 68/227 - (29%)
• Similarity: 93/227 - (40%)
• Gaps: 51/227 - (22%)

  Fly    96 PHVSSSPGSLYHPYAQLFASKRKSSGFSNYEGCYPSPPLSANPNSQQLPPIHNLYGSPVVGGLPL 160
            |:...||..:.|.:..:..  ..|:|.|..:|.|.|....:.|           .|.|.|..:
Human    26 PNQQMSPSPMSHGHYSMHC--LHSAGHSQPDGAYSSASSFSRP-----------LGYPYVNSV-- 75

  Fly   161 PEPGSFCTSPSASS------SASLDYTNNFDEPQGKRFKHESSCSPNSSPLKNHSSGGPVEITPL 219
               .|..:||..||      ||||..:         |.:...:.|..|:.::    ||.|.
Human    76 ---SSHASSPYISSVQSYPGSASLAQS---------RLEDPGADSEKSTVVE----GGEVR---- 120

  Fly   220 INDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKK 284
            .|......::.||.::|.||..|.|.|....||:...|.|:|..|.|::.||||||||:|.|.||
Human   121 FNGKGKKIRKPRTIYSSLQLQALNRRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKK 185

  Fly   285 ----GGSE---SPTFNLSTNSNGSPQASPVSP 309
                ||:.   |...|....|.|||   ||.|
Human   186 LMKQGGAALEGSALANGRALSAGSP---PVPP 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	25/55 (45%)
DLX1	NP_835221.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		3/11 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..118		6/35 (17%)
		Homeodomain	129..185	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..230		7/14 (50%)