Protein Alignment ind and GSX2

DIOPT Version :9

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_573574.2
• Gene: GSX2 / 170825
• HGNCID: 24959
• Length: 304
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 107/378 - (28%)
• Similarity: 132/378 - (34%)
• Gaps: 166/378 - (43%)

  Fly     1 MSRSFLMDSLL---SDRP----------------------------------------------- 15
            |||||.:|||:   :.||
Human     1 MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPGCPSRKSGAFCVCPLCV 65

  Fly    16 --NLSQKKEKLGS----PGGSPTAAAAVAAAAMLPSIPMLPYP-ASYVGSYLFSLGI-------- 65
              :|...:..:|:    .|...|.|.....|....::|:|... :|..|...|...:
Human    66 TSHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKGQFSSAPGDAQFCPRVNHAHHHHH 130

  Fly    66 --QQQQQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHPYAQLFASKRKSSGFSNYEGC 128
              |......|.||..:||||||||||||         :..:|.||.
Human   131 PPQHHHHHHQPQQPGSAAAAAAAAAAAA---------AAAALGHPQ------------------- 167

  Fly   129 YPSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFDEPQGKRFK 193
                                 :.:||            ||:.          |.|..:|  :||.
Human   168 ---------------------HHAPV------------CTAT----------TYNVADP--RRFH 187

  Fly   194 HESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRI 258
            ..:....::|.:.|                   .||:|||||||||||||||||.|.||||||||
Human   188 CLTMGGSDASQVPN-------------------GKRMRTAFTSTQLLELEREFSSNMYLSRLRRI 233

  Fly   259 EIANRLRLSEKQVKIWFQNRRVKQKKGGSESPTFNLSTNSNGSPQASPVSPQV 311
            |||..|.||||||||||||||||.||.|.       .|..|.......|..||
Human   234 EIATYLNLSEKQVKIWFQNRRVKHKKEGK-------GTQRNSHAGCKCVGSQV 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeobox	231..283	CDD:278475	46/51 (90%)
GSX2	NP_573574.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..151		8/34 (24%)
		Homeobox	206..258	CDD:306543	46/51 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..304

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I7182
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1341872at2759
OrthoFinder	1	1.000	-	-		FOG0005158
OrthoInspector	1	1.000	-	-		otm40425
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5146
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.940