DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ind and Hoxd3

DIOPT Version :9

Sequence 1:	NP_996087.2	Gene:	ind / 2768974	FlyBaseID:	FBgn0025776	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_034598.2	Gene:	Hoxd3 / 15434	MGIID:	96207	Length:	433	Species:	Mus musculus

Alignment Length:	281	Identity:	93/281 - (33%)
Similarity:	127/281 - (45%)	Gaps:	69/281 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 GSYLFSLGIQQQQQQQQQQQQHAAAAAAA-----AAAAAALQQHPHVSSSP-GSLYHPYAQLFAS 115
            |.|.:|............|.....|||.:     .::|.::|     ||:| .:..|..|:|..|
Mouse    30 GGYGYSKATDTYGYSTPHQPYPPPAAANSLDSDYPSSACSIQ-----SSAPLRAPAHKGAELNGS 89

  Fly   116 -KRKSSGFSNYEGCYPSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPE----PGSFCTSP----- 170
             .|..:|.|...|....||   ..||:|.||      .|     |.|.    |.|..|:|
Mouse    90 CMRPGTGNSQGGGGGNQPP---GLNSEQQPP------QP-----PPPPPPTLPPSSPTNPGSGVP 140

  Fly   171 --------SASSSASLDYTNNFD--EPQGKRFKHESSCSPNSSPLKNHSSGGPVEITPLINDYAD 225
                    |||||:|......|.  :...:..|.::||:.:....::.|..||
Mouse   141 AKKTKGGLSASSSSSTISKQIFPWMKESRQNSKQKNSCATSGENCEDKSPPGP------------ 193

  Fly   226 SSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQK-----KG 285
            :|||:|||:||.||:|||:||..|.||.|.||:|:||.|.|:|:|:||||||||:|.|     ||
Mouse   194 ASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQKAKG 258

  Fly   286 GSESPTFNLSTNSNGSPQASP 306
            ...||       :..||:.||
Mouse   259 ILHSP-------AGQSPERSP 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeobox	231..283	CDD:278475	34/51 (67%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	44..198		46/184 (25%)
		Antp-type hexapeptide	161..166		1/4 (25%)
		Homeobox	199..251	CDD:278475	34/51 (67%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	258..280		7/22 (32%)
		DUF4074	370..431	CDD:290032
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..433
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810