DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ind and Hoxa3

DIOPT Version :9

Sequence 1:	NP_996087.2	Gene:	ind / 2768974	FlyBaseID:	FBgn0025776	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_034582.1	Gene:	Hoxa3 / 15400	MGIID:	96175	Length:	443	Species:	Mus musculus

Alignment Length:	267	Identity:	88/267 - (32%)
Similarity:	114/267 - (42%)	Gaps:	55/267 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 AAAAAAAALQQHPHVSS----SPGSLYHPYAQLFASKRKSSGFSN----YEGCY------PS-PP 133
            ||...|....|.|:..|    :.|..||..|....|...:.|...    .|.|.      || ||
Mouse    20 AANGFAYNASQQPYAPSAALGTDGVEYHRPACSLQSPASAGGHPKTHELSEACLRTLSGPPSQPP 84

  Fly   134 LSANPNSQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFDEPQGKRFKHESSC 198
            ....|   .|||      .|.....|.|:|......|.|.:.|:....::...||... .:.:..
Mouse    85 GLGEP---PLPP------PPPQAAPPAPQPPQPPPQPPAPTPAAPPPPSSVSPPQSAN-SNPTPA 139

  Fly   199 SPNSSPLKNHSSGGPVEITPLINDYAD-------------------------SSKRIRTAFTSTQ 238
            |...|||.|..:.|. :|.|.:.:...                         ||||.|||:||.|
Mouse   140 STAKSPLLNSPTVGK-QIFPWMKESRQNTKQKTSGSSSGESCAGDKSPPGQASSKRARTAYTSAQ 203

  Fly   239 LLELEREFSHNAYLSRLRRIEIANRLRLSEKQVKIWFQNRRVKQKKGGSESPTFNLSTNSNG-SP 302
            |:|||:||..|.||.|.||:|:||.|.|:|:|:||||||||:|.||   :.....:.|:|.| ||
Mouse   204 LVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRRMKYKK---DQKGKGMLTSSGGQSP 265

  Fly   303 QASPVSP 309
            ..|||.|
Mouse   266 SRSPVPP 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeobox	231..283	CDD:278475	34/51 (67%)
Hoxa3	NP_034582.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	74..151		22/86 (26%)
		Antp-type hexapeptide	156..161		2/4 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	163..197		4/33 (12%)
		COG5576	<182..309	CDD:227863	49/94 (52%)
		Homeobox	196..249	CDD:365835	34/52 (65%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..354		11/28 (39%)
		DUF4074	378..441	CDD:372548
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	401..443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810