Protein Alignment ind and Hhex

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_032271.1
• Gene: Hhex / 15242
• MGIID: 96086
• Length: 271
• Species: Mus musculus
• Alignment Length: 236
• Identity: 60/236 - (25%)
• Similarity: 93/236 - (39%)
• Gaps: 73/236 - (30%)

  Fly    95 HPHVSSSPG---SLYHPYAQLFASKRKSSGFSNYEGCYPSP-----------------PLSANPN 139
            ||..:::|.   .||.|...|             :..:|:|                 |...:||
Mouse     5 HPGPAAAPAVGVPLYAPTPLL-------------QPAHPTPFYIDDILGRGPAAPTPTPTLPSPN 56

  Fly   140 SQQLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASL-----------------DYTNNFDEP 187
            | ....:.:.|.:||..  |.|...:|...|:|:.:|:.                 |||:..
Mouse    57 S-SFTSLVSSYRTPVYE--PTPVHPAFSHHPAAALAAAYGPSGFGGPLYPFPRTVNDYTHAL--- 115

  Fly   188 QGKRFKHESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYL 252
                .:|:        ||     |.|:..:|.:.......|..:..|::.|.:|||::|....||
Mouse   116 ----LRHD--------PL-----GKPLLWSPFLQRPLHKRKGGQVRFSNDQTVELEKKFETQKYL 163

  Fly   253 SRLRRIEIANRLRLSEKQVKIWFQNRRVKQKKGGSESPTFN 293
            |...|..:|..|:|||:|||.||||||.|.::...|:|..|
Mouse   164 SPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENPQSN 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	26/55 (47%)
Hhex	NP_032271.1	Interaction with SOX13. /evidence=ECO:0000250|UniProtKB:Q03014	1..138		31/168 (18%)
		Required for WNT signaling induction. /evidence=ECO:0000250|UniProtKB:Q03014	138..271		29/67 (43%)
		Homeodomain	143..195	CDD:459649	25/51 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..271		3/10 (30%)