Protein Alignment ind and Nkx6-2

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_899071.2
• Gene: Nkx6-2 / 14912
• MGIID: 1352738
• Length: 277
• Species: Mus musculus
• Alignment Length: 273
• Identity: 71/273 - (26%)
• Similarity: 97/273 - (35%)
• Gaps: 88/273 - (32%)

  Fly    27 PGGSPTAAAAVAA----AAMLPSIPMLPY----PASYVGSYLFSLGIQQQQQQQQQQQQHAAA-- 81
            ||....::|.:||    |.|..|  :.||    ||.:....|.|||     .|......|..:
Mouse     6 PGAFVLSSAPLAALHNMAEMKTS--LFPYALQGPAGFKTPALGSLG-----AQLPLGTPHGISDI 63

  Fly    82 -----AAAAAAAAAALQQHPHVSSSPGSLYHPYAQLFASKRKSSGFSNYEGCYPSPPLSANPNSQ 141
                 .||......:|.:...::||.|..:.|.|.:...             ||. ||:..|..
Mouse    64 LGRPVGAAGGGLLGSLPRLNGLASSAGVYFGPAAAVARG-------------YPK-PLAELPGR- 113

  Fly   142 QLPPIHNLYGSPVVGGLPLPEPGSFCTSPSASSSASLDYTNNFDEPQGKRFKHESSCSPNSSPLK 206
              |||   :...||.|.|..:|.   .:.||.:...||       ..||               |
Mouse   114 --PPI---FWPGVVQGSPWRDPR---LAGSAQAGGVLD-------KDGK---------------K 148

  Fly   207 NHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRIEIANRLRLSEKQV 271
            .||                     |..|:..|:..||:.|....||:...|..:|..|.::|.||
Mouse   149 KHS---------------------RPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQV 192

  Fly   272 KIWFQNRRVKQKK 284
            |:||||||.|.:|
Mouse   193 KVWFQNRRTKWRK 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	22/55 (40%)
Nkx6-2	NP_899071.2	Homeodomain	147..205	CDD:459649	26/93 (28%)