Protein Alignment ind and CDX4

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: NP_005184.1
• Gene: CDX4 / 1046
• HGNCID: 1808
• Length: 284
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 71/254 - (27%)
• Similarity: 110/254 - (43%)
• Gaps: 59/254 - (23%)

  Fly   102 PGSLYHPYAQLFASKRKSSG---------------FSNYEGCYPSPPLSANPNSQQLPPIHNLYG 151
            ||:|..|.....|....:.|               ||:|.| ||..| |.:|:...|    .::|
Human    15 PGTLMSPGGDGTAGTGGTGGGGSPMPASNFAAAPAFSHYMG-YPHMP-SMDPHWPSL----GVWG 73

  Fly   152 SP----------------VVGGLPLPE----PGSFCTSP--------SASSSASLDYTNNFDEPQ 188
            ||                .:|.:|:.:    |.:||::.        ..:|.:||.     .:..
Human    74 SPYSPPREDWSVYPGPSSTMGTVPVNDVTSSPAAFCSTDYSNLGPVGGGTSGSSLP-----GQAG 133

  Fly   189 GKRFKHESSCSPNSSPLKN-HSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYL 252
            |.....::..:..|||.:: ||....:..|..:.....:.::.|..:|..|.||||:||..|.|:
Human   134 GSLVPTDAGAAKASSPSRSRHSPYAWMRKTVQVTGKTRTKEKYRVVYTDHQRLELEKEFHCNRYI 198

  Fly   253 SRLRRIEIANRLRLSEKQVKIWFQNRRVKQKKGGSESPTFNLSTNSNGSPQ--ASPVSP 309
            :..|:.|:|..|.|||:||||||||||.|::|  ......:...||.||.|  :..:||
Human   199 TIQRKSELAVNLGLSERQVKIWFQNRRAKERK--MIKKKISQFENSGGSVQSDSDSISP 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	29/55 (53%)
CDX4	NP_005184.1	Caudal_act	13..170	CDD:461413	34/165 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..40		6/24 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..155		7/39 (18%)
		Homeodomain	175..230	CDD:459649	29/54 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..259		7/18 (39%)