DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ind and Hoxb2

DIOPT Version :9

Sequence 1:	NP_996087.2	Gene:	ind / 2768974	FlyBaseID:	FBgn0025776	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	NP_598793.2	Gene:	Hoxb2 / 103889	MGIID:	96183	Length:	354	Species:	Mus musculus

Alignment Length:	200	Identity:	67/200 - (33%)
Similarity:	95/200 - (47%)	Gaps:	33/200 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   144 PPIHNLYGSPVVGGLPLPEPGS---------------FCTSPSASSSASLDYTNNFDEPQGKRFK 193
            ||:...:.|..:|...|..|||               ...:|.|.....:....:..:|.    :
Mouse    47 PPLEQTFPSLQLGASTLQRPGSQKQAGDGPALRSPPPLPVAPPAPEFPWMKEKKSTKKPS----Q 107

  Fly   194 HESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLSRLRRI 258
            ..:|.||.:|.::....|.|.:...|.......|:|:|||:|:|||||||:||..|.||.|.||:
Mouse   108 SAASPSPAASSVRASEVGSPSDGPGLPECGGSGSRRLRTAYTNTQLLELEKEFHFNKYLCRPRRV 172

  Fly   259 EIANRLRLSEKQVKIWFQNRRVKQKK---------GGSESPTFNLSTNSNGSPQASP-VSP-QVK 312
            |||..|.|:|:|||:||||||:|.|:         |....|:   :.:..|.|...| ||| .|.
Mouse   173 EIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPEGEPGGPS---AQDDAGEPAEEPTVSPGDVA 234

  Fly   313 VHELK 317
            .|.|:
Mouse   235 THRLR 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeobox	231..283	CDD:278475	35/51 (69%)
Hoxb2	NP_598793.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..143		19/99 (19%)
		Antp-type hexapeptide	92..97		0/4 (0%)
		Homeobox	145..197	CDD:278475	35/51 (69%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	193..231		10/40 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	246..295
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810