Protein Alignment ind and en2

DIOPT Version :10

• Sequence 1: NP_996087.2
• Gene: ind / 2768974
• FlyBaseID: FBgn0025776
• Length: 320
• Species: Drosophila melanogaster
• Sequence 2: XP_002932525.1
• Gene: en2 / 100498251
• XenbaseID: XB-GENE-853108
• Length: 266
• Species: Xenopus tropicalis
• Alignment Length: 322
• Identity: 74/322 - (22%)
• Similarity: 106/322 - (32%)
• Gaps: 117/322 - (36%)

  Fly     4 SFLMDSLLSDRPNLSQKKEKLGSPGGSPTAAAAVAAAAMLPSIPMLPYPASYVGSYLFSLGIQQQ 68
            :|.:|::|  ||...::||                                         ||..|
 Frog    41 NFFIDNIL--RPEFGRRKE-----------------------------------------GISHQ 62

  Fly    69 QQQQQQQQQHAAAAAAAAAAAAALQQHPHVSSSPGSLYHPYAQLFASKR---------KSSGFSN 124
            .:....:...|.:.|.:|        |...:::.|:.......|...|:         ||.|.:.
 Frog    63 DELFSGRDSGALSGAESA--------HHRANATEGAGGSKAITLTGDKKSDIAMEESLKSRGHNG 119

  Fly   125 YEGCYPSPPLSANPNSQQLPPIHNLYGSPVVGGLPLPEPG-SFCTSPSASSSASLDYTNNFDEPQ 188
                  ...||::.:|.|        .|......|:..|. .:||
 Frog   120 ------DHSLSSDSDSSQ--------ASSKTSQQPMLWPAWVYCT-------------------- 150

  Fly   189 GKRFKHESSCSPNSSPLKNHSSGGPVEITPLINDYADSSKRIRTAFTSTQLLELEREFSHNAYLS 253
              |:....|..|.|...|..::          .......||.|||||:.||..|:.||..|.||:
 Frog   151 --RYSDRPSSGPRSRKPKKKTT----------TTVTKEDKRPRTAFTADQLQRLKAEFQTNRYLT 203

  Fly   254 RLRRIEIANRLRLSEKQVKIWFQNRRVKQKK--GGSES--------PTFNLSTNSNGSPQAS 305
            ..||..:|..|.|:|.|:||||||:|.|.||  |...|        ..:|.||.|..|...|
 Frog   204 EQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNSLALHLMAQGLYNHSTTSKDSKSDS 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeodomain	228..284	CDD:459649	30/55 (55%)
en2	XP_002932525.1	Homeodomain	178..234	CDD:459649	30/55 (55%)
		Engrail_1_C_sig	235..265	CDD:431338	7/29 (24%)