DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ind and hoxc3

DIOPT Version :9

Sequence 1:	NP_996087.2	Gene:	ind / 2768974	FlyBaseID:	FBgn0025776	Length:	320	Species:	Drosophila melanogaster
Sequence 2:	XP_002936696.1	Gene:	hoxc3 / 100190990	XenbaseID:	XB-GENE-5997986	Length:	394	Species:	Xenopus tropicalis

Alignment Length:	254	Identity:	82/254 - (32%)
Similarity:	112/254 - (44%)	Gaps:	58/254 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 PGSLYHPYAQLFASKRKSSGFSNYEGC-------YPS-----PPLSANPNSQQLPPIHNLYGSPV 154
            |.||::..:..|.    ..||....|.       |||     ||....|::......|.  |...
Frog     4 PKSLFYDNSASFG----GCGFQGNNGMGYLGQQDYPSEDDYQPPFCLPPDTANGSASHK--GEHS 62

  Fly   155 VGGL---------------------PLPEPGS--FCTSPSASSSASLDYTNNFDEPQGKR----- 191
            :.|:                     |||:..|  .|||..::...|.|.|:...:.:|..
Frog    63 IKGIDFHLSEVSEQAQQPKSPNSDSPLPKSASTQSCTSKKSTGPVSSDVTSPNKKSKGSNMPKQI 127

  Fly   192 FKHESSCSPNSSPLKNHSSGGPVEITPLIND--YADSSKRIRTAFTSTQLLELEREFSHNAYLSR 254
            |........||...|  .:..|.:..|.::.  .:.:|||.|||:|::||:|||:||..|.||.|
Frog   128 FPWMKETRQNSKQKK--QAPPPADDAPAVDSSFLSSASKRARTAYTNSQLVELEKEFHFNRYLCR 190

  Fly   255 LRRIEIANRLRLSEKQVKIWFQNRRVKQK-----KGGSESPTFNLSTNSNGSPQASPVS 308
            .||:|:|..|.|||:|:||||||||:|.|     |||..||. .||.:|  ||...|.|
Frog   191 PRRLEMAKLLNLSERQIKIWFQNRRMKFKKDHKGKGGGGSPG-GLSPSS--SPSLMPYS 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ind	NP_996087.2	Homeobox	231..283	CDD:278475	33/51 (65%)
hoxc3	XP_002936696.1	Homeobox	167..220	CDD:395001	33/52 (63%)
hoxc3	XP_002936696.1	DUF4074	335..392	CDD:404218
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910