DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33490 and Efhc1.1

DIOPT Version :9

Sequence 1:	NP_996047.1	Gene:	CG33490 / 2768970	FlyBaseID:	FBgn0053490	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_573075.1	Gene:	Efhc1.1 / 32528	FlyBaseID:	FBgn0030691	Length:	793	Species:	Drosophila melanogaster

Alignment Length:	385	Identity:	75/385 - (19%)
Similarity:	130/385 - (33%)	Gaps:	99/385 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 RYIERNPGIRAAGLTSTVQFNGAKDCLFVVSLEEEAEDRIRALCRRSRPKPAKRTPKLPTHQIGD 70
            ||:.|    ..|.:.||::.|..:  :||:|.         .||.             .|.||.:
  Fly   432 RYVLR----FGAKMLSTIKANCER--IFVISY---------YLCD-------------DTLQIQE 468

  Fly    71 ILNNENPGLFAELQNKFRENMFHKKPGLGEARETNSKPSYVTNLSHTFGKITQSNCNDSLYSIVL 135
            |....:..|..|...:.|..:    |  |:.|.:..:|.|....:...|  :..:..|.::.||
  Fly   469 IAVRNSGFLGGEFMKRTRLEL----P--GQERFSCKQPQYYMPWNFFVG--STMSLKDFIFHIV- 524

  Fly   136 PPKSAEQVNREYGEYHDKHIISHNHYFPAEQI----NRRYSKPFNRFNTFGLPPTLDPSGIKMKH 196
               ||::....|.|:|.:       .||...:    .:..|...||...|......|.:.::.|.
  Fly   525 ---SADEYTLMYMEHHPE-------IFPHANVGVIMEKVKSALQNRMAEFVGSCVPDCTDLEKKR 579

  Fly   197 CLEEGEEHLK--IVKKPQKDIDDRTKGPLGKKYSWYPYQIPENMTFGRTLPRETDVRSLLEYTSP 259
            .:....|..|  ::......|.|.....|.:.:|                         .|.:.|
  Fly   580 DVFVSFESFKGALISIMGNQISDHEIISLCRHFS-------------------------AEKSQP 619

  Fly   260 SIKSEKLAIAVSHLNMLRKMLQERDDFNMNQVISALGKKDTEGQRQLPLDEVINVLHKLSIPADA 324
            :........|.:||.:.|.:...|||     ::......:...|..||..:|.:.|....:|...
  Fly   620 NACDRSTVRAAAHLELKRTLWNARDD-----LMEHFHHINPTNQPFLPEVKVRSALRGCRLPFSL 679

  Fly   325 EKIRNAASHFQLFVDEGCCSEKVKYEELCDLLSIL--------KSLPLIGSITPMPKVTY 376
            |.|.|..|    .::...|.:    .|:|||::.:        ..||:..:....||:.:
  Fly   680 ELIDNILS----ILNRNECDD----IEVCDLMNFIDVSCGKGCDMLPVNHAFELCPKIPF 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33490	NP_996047.1	None
Efhc1.1	NP_573075.1	DM10	82..189	CDD:128921
		DUF1126	110..142	CDD:284078
		DM10	232..370	CDD:128921
		DUF1126	256..288	CDD:284078
		DM10	431..538	CDD:128921	32/145 (22%)
		DUF1126	454..486	CDD:284078	10/53 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12086
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100