Protein Alignment CG33490 and Efhb

DIOPT Version :9

• Sequence 1: NP_996047.1
• Gene: CG33490 / 2768970
• FlyBaseID: FBgn0053490
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_766085.2
• Gene: Efhb / 211482
• MGIID: 3045296
• Length: 853
• Species: Mus musculus
• Alignment Length: 606
• Identity: 147/606 - (24%)
• Similarity: 231/606 - (38%)
• Gaps: 144/606 - (23%)

  Fly     5 GRYIERNPGIRAAGLTSTVQFNGAKDCLFVVSLEEEAEDRIRALCRRSRPKPAKR---------- 59
            |::.:|.|...:||....|.:..| .||            ...|.|...|..||:
Mouse   272 GKFFDRVPCWPSAGKVKPVGYRVA-TCL------------TEKLPRLMTPPEAKKYFNFRYPPAG 323

  Fly    60 ----------TPKLP---TH--------QIGDILNNENPGLFAELQNKFRENMF--HKKPGLGEA 101
                      .|::.   ||        .:|.::|.:....|.:.....:|:::  |::..||::
Mouse   324 AERVFYGRANDPQIAPYLTHGLRSKISIPMGSLINPQPITTFQQKIKDKKESIYFSHQRAPLGKS 388

  Fly   102 R-ETNSKPSYVTNLSHTFGKITQSNCNDSLYSIVLPPKSAEQVNREYGEYHDKHIISHNHYFPAE 165
            . :|...|..:..::.|.|..|....  |:...|.|.||.|.|.:|..|.||.:.:|||.||..|
Mouse   389 HDQTPGLPKGMDVINTTLGTPTIREL--SVRDTVNPSKSFEDVLKEGQEGHDLYTVSHNDYFAGE 451

  Fly   166 QINRRYS-KPFNRFNTFGLPPTLDPSG---IKMKHCLEE--GEEHLKIVKKPQKDIDDRTKGPLG 224
            ..||:|: ..|:|||.:|:|......|   .|..|.|.|  .|...|||.|...|..::.:..||
Mouse   452 AKNRKYNPASFHRFNLYGIPTPHFNDGRTMAKALHWLHELQMERGAKIVSKRVDDFKEKFQHKLG 516

  Fly   225 KKYSWYP----YQIPENMTFGRTL-PRETDVRSLLEYTSPSI----KSEKLAIAVSHLNMLRKML 280
            |...  |    ..:|...|||..| |.|.....|:.|.||..    |..:.|:..:..:.|:|.
Mouse   517 KVLD--PIAETMNVPPGHTFGSCLHPEEYGAGDLIHYRSPDEYLRGKDHQRAVVAAARHHLKKF- 578

  Fly   281 QERDDFNMNQVISALGKKDTEGQRQLPLDEVIN--VLHKLSIPADAEKIRNAASHFQLFVD---E 340
             ...:|:..||  |....|.:|      |.||:  .||:..:.|:....:....|...:.|   :
Mouse   579 -NHQNFDTLQV--AFRHYDKKG------DGVIDRAELHEACVQANLHLDKMLLDHLFDYCDVDQD 634

  Fly   341 GCCSEKVKYEELCDLLSILKSLPL---------IGSITPMPKVTYNQDTAYRQLCADLMKKP--- 393
            |.    :.|.|..:.|:....:||         .|.......||   ||:..:....|:..|
Mouse   635 GL----INYLEFANFLNWKDRIPLKEHEKRVVVKGKKPDCENVT---DTSMGEAEPSLLINPEDI 692

  Fly   394 -PEGP-------------------QFKTAKKASIKQDMNAAP---FKDFNSPQKAPIEQDMDETR 435
             |:.|                   |:||. .:.|...:.|.|   ...|..|   .|..|:...|
Mouse   693 VPKEPGSSEETLRTIQRPGDKVSHQYKTT-SSEINAVVGAVPSMCHPIFGVP---TIRSDISAPR 753

  Fly   436 SRDYKTSQKTPIQQDM----DDTRVGDVINPEFSTLCGLWPSDFKALRSKDEIERIFKDI---VS 493
            .|..         .||    |:.....:::|...:..|::..||...|||:||..|..:|   :|
Mouse   754 IRRV---------SDMNNYGDEGNAYSLLHPSIFSQKGVFERDFFKTRSKEEISDILTNIGVKLS 809

  Fly   494 KEDFQTIWLSLMDEQKDQNEM 514
            ||:|:.:| :|..::..:.|:
Mouse   810 KEEFENVW-NLASKKHQRGEV 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33490	NP_996047.1	None
Efhb	NP_766085.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..31
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..266
		EF-hand_7	586..646	CDD:290234	16/71 (23%)
		EFh	586..646	CDD:238008	16/71 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2CJU2
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	94	1.000	Inparanoid score	I5054
Isobase	1	0.950	-	0	Normalized mean entropy	S8373
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42829
orthoMCL	1	0.900	-	-		OOG6_104929
Panther	1	1.100	-	-	O	PTHR12086
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.770