Protein Alignment CG33490 and EFHB

DIOPT Version :9

• Sequence 1: NP_996047.1
• Gene: CG33490 / 2768970
• FlyBaseID: FBgn0053490
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_653316.3
• Gene: EFHB / 151651
• HGNCID: 26330
• Length: 833
• Species: Homo sapiens
• Alignment Length: 617
• Identity: 138/617 - (22%)
• Similarity: 230/617 - (37%)
• Gaps: 166/617 - (26%)

  Fly     5 GRYIERNPGIRAAGLTSTVQFNGAKDCLFVVSLEEEAEDRIRALCRRSRPKPAKR---------- 59
            |::.:|.|...:||....|.:..| .||            ...|.|...|..||:
Human   252 GKFFDRTPCWPSAGKVIPVGYRVA-TCL------------TEKLPRLITPPEAKKYFNFRYPPAG 303

  Fly    60 --------------TPKLPTHQIG---DILNNE--NPGLFAELQNKFREN-----MFHKKPGLGE 100
                          .|.| ||.|.   .:|.|.  ||......|.|.::.     :.:::..||:
Human   304 VERVFYGRANDPQIAPYL-THGIRSKISVLANTLINPQPITTFQQKIKDKKESIYLSNRRAPLGK 367

  Fly   101 AR-ETNSKPSYVTNLSHTFGK--ITQSNCNDSLYSIVLPPKSAEQVNREYGEYHDKHIISHNHYF 162
            :. :....|..:...:.|||.  |.:.:..|    :|.||||.|:|.:|..|.||.:::|||.|:
Human   368 SHDQAPGLPKGMDTTNTTFGTAVIKEYSAKD----VVNPPKSYEEVFKEGNEGHDLYVVSHNDYY 428

  Fly   163 PAEQINRRYS-KPFNRFNTFGLPPTLDPSGIKMKHCLE-----EGEEHLKIVKKPQKDIDDRTKG 221
            ..|..||:|: ..|:|.:.:|:|......|..|...|.     :.:...|.|.|...|..::.:.
Human   429 AGEAKNRKYNPSSFHRCSVYGVPTPHFNDGRAMAKSLYWLHELQMKRGAKFVSKRADDFKEKFQH 493

  Fly   222 PLGKKYSWYP----YQIPENMTFGRTL-PRETDVRSLL------EYTSPSIKSEKLAIAVSHLNM 275
            .||:...  |    ..:|.:.|||..| |.|..|..|:      ||.....:...|..||.|  .
Human   494 KLGRVLD--PIAETMNVPPDCTFGACLRPEEYGVGDLIHNRLPDEYLRGKDRQRALIAAVRH--H 554

  Fly   276 LRKMLQERDDFNMNQVISALGKKDTEGQRQLPLDEVINVLHKLSIPADAEKIRNAASHFQLFVDE 340
            |:|:..::.|    .:::|....|.:|...:..||:.....:.::..| :|:.:     |||  :
Human   555 LKKVNYQKFD----TLLAAFRHYDKKGDGMIDKDELQEACDQANLSLD-DKLLD-----QLF--D 607

  Fly   341 GCCSEK---VKYEELCDLLS-----ILKSLP---LIGSITP-----------MPKVTYNQDTAYR 383
            .|..:.   :.|.|..:.|:     :||...   :|....|           .|:.|
Human   608 YCDVDNDGFINYLEFANFLNWKDKMLLKEYEERVIIKGRKPDCVNPTEANVEEPEQT-------- 664

  Fly   384 QLCADLMKKPPE------GPQFKTAKKASIKQDMNAAPFKDFNSPQKA----------------P 426
                 |:.||.:      |...||.:......|..:..:|..:|...|                .
Human   665 -----LLIKPEDIVLKEAGSTEKTLRTLLRPSDKVSNYYKTTSSEINAIVGAIPSTCYPICGVPT 724

  Fly   427 IEQDMDETRSRDYKTSQKTPIQQDMDDTRVGD------VINPEFSTLCGLWPSDFKALRSKDEIE 485
            |..|:...|           |::..|.|..|:      ::.|......|::..||...|||:||.
Human   725 IRSDIPAPR-----------IRRISDRTNYGEEGSAYSLLYPTIFARKGVFERDFFKTRSKEEIA 778

  Fly   486 RIFKDI---VSKEDFQTIWLSLMDEQKDQNEM 514
            .|..:|   :|.|:|:.:| :|..::..:.|:
Human   779 EILCNIGVKLSDEEFENVW-NLASKKHHRGEV 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33490	NP_996047.1	None
EFHB	NP_653316.3	EF-hand_7	566..626	CDD:290234	13/67 (19%)
		EFh	566..626	CDD:238008	13/67 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	94	1.000	Inparanoid score	I5070
Isobase	1	0.950	-	0	Normalized mean entropy	S8373
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1016066at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_104929
Panther	1	1.100	-	-	O	PTHR12086
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.880