DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33288 and rcc1l

DIOPT Version :9

Sequence 1:	NP_996136.2	Gene:	CG33288 / 2768968	FlyBaseID:	FBgn0053288	Length:	1115	Species:	Drosophila melanogaster
Sequence 2:	NP_001076272.1	Gene:	rcc1l / 555972	ZFINID:	ZDB-GENE-060526-370	Length:	451	Species:	Danio rerio

Alignment Length:	286	Identity:	59/286 - (20%)
Similarity:	99/286 - (34%)	Gaps:	72/286 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SGAIFTLGK------------------SHLAENTQSYFYIKNDPVKRLISGPNQSAVICESGRLF 52
            |..:|::|.                  ||:....:.:    :..|.::..|.:.|..:.:.|.:|
Zfish   179 SEGVFSMGSNTFGQCGRKIVEDEVYSGSHVVHKIEGF----DSRVIQVACGQDHSLFLTDRGSVF 239

  Fly    53 VWGENHYGQLGIGGHGGAS------GKKGGGSHN---------------------GNGDI----- 85
            ..|....||.|:|.|..||      |...|.:..                     ||.:.
Zfish   240 ACGWGADGQTGLGHHNKASCPVPVGGDLAGVTVQQVATYGDCSLAVSTDGQVFGWGNSEYLQLAS 304

  Fly    86 VTKPTCVKALKTLGLK----ICDVAFGNHWAVMLTHSNEIFFTGRNIFPEDTHVAQHFTSAQVDQ 146
            ||:.|.:.:.:.|.||    |...|.|.....:|....::|..|..|..:...:::   ||..::
Zfish   305 VTESTQISSPRLLPLKGVGRIRQAACGGTQVAVLNEDGDVFVWGFGILGKGPKLSE---SAIPER 366

  Fly   147 QPCAIIRKPFRLEEFDDYLSKNEETDNFMTVQAGKEHFAVLTTTGRLIGCGSNAQLQLGELEADY 211
            .|...    |...||:       .|....:::.|..|||.:|..|.|...|.|.:..||..:.|.
Zfish   367 VPATF----FGRSEFN-------PTVKVASIRCGLSHFAAVTDGGELFVWGKNVRGCLGIGKHDD 420

  Fly   212 DGHPVEIRLDAPVQQFTCGPESTLVL 237
            ...|..:.:...|....||.:..:.|
Zfish   421 QYFPWRVTVPGHVTDVACGVDHMVAL 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33288	NP_996136.2	ATS1	5..>260	CDD:227511	59/286 (21%)
rcc1l	NP_001076272.1	RCC1	52..108	CDD:278826
		RCC1_2	165..192	CDD:290274	3/12 (25%)
		RCC1	182..232	CDD:278826	7/53 (13%)
		RCC1_2	219..248	CDD:290274	6/28 (21%)
		RCC1	236..285	CDD:278826	12/48 (25%)
		RCC1	288..338	CDD:278826	11/49 (22%)
		RCC1_2	383..412	CDD:290274	9/28 (32%)
		RCC1	400..446	CDD:278826	11/45 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594736
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830