DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33288 and rcbtb1

DIOPT Version :9

Sequence 1:	NP_996136.2	Gene:	CG33288 / 2768968	FlyBaseID:	FBgn0053288	Length:	1115	Species:	Drosophila melanogaster
Sequence 2:	NP_956285.1	Gene:	rcbtb1 / 336007	ZFINID:	ZDB-GENE-030131-7951	Length:	531	Species:	Danio rerio

Alignment Length:	470	Identity:	96/470 - (20%)
Similarity:	156/470 - (33%)	Gaps:	168/470 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 KRLI-----SGPNQSAVICESGRLFVWGENHYGQLGIGGHGGASGKKGGGSHNGNGDIVTKPTCV 92
            |:||     |||: ..::.|.|.|:.||.|.|.|||                ||..:....|..|
Zfish    74 KKLISLSYGSGPH-VLLVTEDGELYAWGHNGYSQLG----------------NGTTNQGVSPILV 121

  Fly    93 KALKTLGLKICDVAFGNHWAVMLTHSNEIFFTGRNIF-----------PEDTHVA---------- 136
             :....|.::.:|:.|:|.::.|||..|:|..|.|..           |....|:
Zfish   122 -STNLQGKRVTEVSCGSHHSLALTHEGEVFAWGYNNCGQVGSGSTANQPTPRKVSNCLQNKVIVN 185

  Fly   137 ----QHFTSAQVDQ-----------------------QPCAIIRKPFRLEEFDDYLSKNEETDNF 174
                |..:.|..|.                       .||.:|    .|:.|           ..
Zfish   186 IACGQTSSMAVTDNGEVYGWGYNGNGQLGLGNNGNQLTPCRLI----ALQGF-----------CV 235

  Fly   175 MTVQAGKEHFAVLTTTGRLIGCGSNAQLQLGELEADYDGHPVEIRLDAP--VQQFTC-GPESTLV 236
            :.:.:|..|...||..|.|...|:|...|||.........||::..:..  |:...| ...::..
Zfish   236 LQIASGYAHSLALTDEGLLYAWGANTYGQLGTGNKSNQLSPVQVMTEKERIVEIAACHSTHTSAA 300

  Fly   237 LTATGNLFLTG----------HLNEF-----VFPRFTELQKNLPPTEAIIFMHISKTSEVYIVTN 286
            .|.:|.:::.|          ||..|     ||..|.        |.::::..:|...:.:: |.
Zfish   301 KTQSGQVYMWGQCRGQAIVLPHLTHFASTDDVFACFA--------TPSVMWRMLSMEHDDFL-TV 356

  Fly   287 AGSIYRSFESLRNKSLVFQRFYDYDCEENGPIWKLLKGFSFY---AVLSKANKFFTTFSES--GH 346
            |.|:.:.|::.....|.|.                :.|...:   |||....:.|.:..:|  ..
Zfish   357 AQSLKKEFDNPETSDLEFS----------------IDGKYIHVHKAVLKIRCEHFRSMFQSHWNE 405

  Fly   347 HLKTFREISKFK----------------------NLRLLDIAVG---------DQHVLVQGIP-- 378
            .:|...||.:|.                      .:.|||:|..         .||::.:||.
Zfish   406 DMKEVIEIDQFSYPVYRSFLEFLYTDSVDLPPEDAIGLLDLATSYCENRLKKLCQHIIKRGITVE 470

  Fly   379 -RSSMSSASVNGSAE 392
             ..|:.||::...||
Zfish   471 NAFSLLSAAIRYDAE 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33288	NP_996136.2	ATS1	5..>260	CDD:227511	65/297 (22%)
rcbtb1	NP_956285.1	RCC1	40..90	CDD:278826	6/16 (38%)
		RCC1_2	77..106	CDD:290274	11/29 (38%)
		RCC1	93..143	CDD:278826	17/66 (26%)
		RCC1	146..196	CDD:278826	7/49 (14%)
		RCC1	199..248	CDD:278826	7/63 (11%)
		RCC1	251..299	CDD:278826	11/47 (23%)
		BTB	360..464	CDD:279045	19/119 (16%)
		BTB	371..467	CDD:197585	18/111 (16%)
		SPOP_C_like	467..525	CDD:269810	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900