DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AsnS and ASN2

DIOPT Version :9

Sequence 1:	NP_996132.1	Gene:	AsnS / 2768965	FlyBaseID:	FBgn0270926	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_201306.2	Gene:	ASN2 / 836625	AraportID:	AT5G65010	Length:	579	Species:	Arabidopsis thaliana

Alignment Length:	574	Identity:	254/574 - (44%)
Similarity:	334/574 - (58%)	Gaps:	44/574 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCGIFAIFSRDGEPIPTQILHGSKHSLRELAYRQSGKHRHRGPDSTGVYVNSLEGVAMIHERLRI 65
            ||||.|:..          ...:..:.|......|.:.||||||.:|::  ..|...:.||||.|
plant     1 MCGILAVLG----------CIDNSQAKRSRIIELSRRLRHRGPDWSGLH--CYEDCYLAHERLAI 53

  Fly    66 IGVEMGDQPFVSEDGNLILVANGEIYNYLELSAEIAKKRGSYNPMSDCHVILELYQDYGKDLLQY 130
            |....||||..:||..:.:..||||||:..|..::  |...:...|||.||..||:::|::.:..
plant    54 IDPTSGDQPLYNEDKTVAVTVNGEIYNHKILREKL--KSHQFRTGSDCEVIAHLYEEHGEEFIDM 116

  Fly   131 ITGMFAFALYDRKTKEVLLARDPFGIIPMYVGEDASGNLWVASEMKCLVDTCSKVETFTPGEARF 195
            :.|||||.|.|.:.|..:.|||..||.|:|:|....|::|.|||||.|.|.|.:..:|.||....
plant   117 LDGMFAFVLLDTRDKSFIAARDAIGITPLYIGWGLDGSVWFASEMKALSDDCEQFMSFPPGHIYS 181

  Fly   196 GKVGDFKTCWQFQQSWIKE-VPTQTCELSLLRANLEFAVRSHLQCDVQMGALLSGGVDSSLIASI 259
            .|.|..:. | :...|..| ||:...:..:||...|.||...|..||..|.|||||:||||:|::
plant   182 SKQGGLRR-W-YNPPWYNEQVPSTPYDPLVLRNAFEKAVIKRLMTDVPFGVLLSGGLDSSLVAAV 244

  Fly   260 ATKIMRE----RDPNFRLKTFSVGLRDAPDFQAARSVAKYIDSDHKEIIFEIDEALDGIRDIIYH 320
            |.:.:.:    |....:|.||.:||:.:||.:|.|.||.|:.:.|.|..|.:.:.:|.|.::|||
plant   245 ALRHLEKSEAARQWGSQLHTFCIGLQGSPDLKAGREVADYLGTRHHEFQFTVQDGIDAIEEVIYH 309

  Fly   321 LETYDVTTVRCSLPMLLLARYIKSTGIKMILSGEGADEIFGGYLYFHKAPSYNDFHEELVKRVRQ 385
            :|||||||:|.|.||.|::|.|||.|:||:|||||:|||.||||||||||:..:||||..::::.
plant   310 IETYDVTTIRASTPMFLMSRKIKSLGVKMVLSGEGSDEILGGYLYFHKAPNKKEFHEETCRKIKA 374

  Fly   386 LHLSDCLRANKVAMAKGVELRVPFLDTGFVNHVMQIRPEDKIPGPLNKFGEVQQKRLEKYVLRAA 450
            ||..|||||||...|.|||.||||||..|:|..|.|.||.|:..|       ...|:||:|||.|
plant   375 LHQFDCLRANKSTSAWGVEARVPFLDKEFLNVAMSIDPEWKLIKP-------DLGRIEKWVLRNA 432

  Fly   451 FADN---YLPDEVLWRQKEQFSDGVGYDWIDSIRRVATSHVSDQEFSAAALRFPFNTPTTKEAFY 512
            |.|.   |||..:|:||||||||||||.|||.::..|..||||...|.|:..||.|||.||||:|
plant   433 FDDEERPYLPKHILYRQKEQFSDGVGYSWIDGLKDHANKHVSDTMLSNASFVFPDNTPLTKEAYY 497

  Fly   513 YRCIFAEQFPGESAARTVVRWVPRL------------DWGCPEDPSGRAQ-AVH 553
            ||.||.:.||.:||||..|...|.:            .|....||||||. .||
plant   498 YRTIFEKFFPKQSAARATVPGGPSIACSTAKAVEWDATWSKNLDPSGRAALGVH 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AsnS	NP_996132.1	asnB	1..554	CDD:236513	254/574 (44%)
		AsnB	2..>182	CDD:238364	67/179 (37%)
		Asn_synthase	225..528	CDD:279122	162/309 (52%)
ASN2	NP_201306.2	PLN02549	1..552	CDD:178164	254/574 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	163	1.000	Domainoid score	I1237
eggNOG	1	0.900	-	-		E1_COG0367
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	452	1.000	Inparanoid score	I384
OMA	1	1.010	-	-		QHG62355
OrthoDB	1	1.010	-	-		D782607at2759
OrthoFinder	1	1.000	-	-		FOG0001900
OrthoInspector	1	1.000	-	-		otm3380
orthoMCL	1	0.900	-	-		OOG6_100710
Panther	1	1.100	-	-	LDO	PTHR11772
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1254
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840