DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AsnS and ASN3

DIOPT Version :9

Sequence 1:	NP_996132.1	Gene:	AsnS / 2768965	FlyBaseID:	FBgn0270926	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_196586.1	Gene:	ASN3 / 830888	AraportID:	AT5G10240	Length:	578	Species:	Arabidopsis thaliana

Alignment Length:	574	Identity:	251/574 - (43%)
Similarity:	333/574 - (58%)	Gaps:	45/574 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCGIFAIFSRDGEPIPTQILHGSKHSLRELAYRQSGKHRHRGPDSTGVYVNSLEGVAMIHERLRI 65
            ||||.|:..          ...:..:.|......|.:.||||||.:|::  ..|...:.||||.|
plant     1 MCGILAVLG----------CVDNSQAKRSRIIELSRRLRHRGPDWSGLH--CYEDCYLAHERLAI 53

  Fly    66 IGVEMGDQPFVSEDGNLILVANGEIYNYLELSAEIAKKRGSYNPMSDCHVILELYQDYGKDLLQY 130
            :....||||..:||..:.:..||||||:..|...:  |...:...|||.||..||:::|::.:..
plant    54 VDPTSGDQPLYNEDKTIAVTVNGEIYNHKALRENL--KSHQFRTGSDCEVIAHLYEEHGEEFVDM 116

  Fly   131 ITGMFAFALYDRKTKEVLLARDPFGIIPMYVGEDASGNLWVASEMKCLVDTCSKVETFTPGEARF 195
            :.|||||.|.|.:.|..:.|||..||.|:|:|....|::|.|||||.|.|.|.:...|.||....
plant   117 LDGMFAFVLLDTRDKSFIAARDAIGITPLYIGWGLDGSVWFASEMKALSDDCEQFMCFPPGHIYS 181

  Fly   196 GKVGDFKTCWQFQQSWIKE-VPTQTCELSLLRANLEFAVRSHLQCDVQMGALLSGGVDSSLIASI 259
            .|.|..:. | :...|..| ||:...:..::|...|.||...|..||..|.|||||:||||:||:
plant   182 SKQGGLRR-W-YNPPWFSEVVPSTPYDPLVVRNTFEKAVIKRLMTDVPFGVLLSGGLDSSLVASV 244

  Fly   260 ATKIMRERDP----NFRLKTFSVGLRDAPDFQAARSVAKYIDSDHKEIIFEIDEALDGIRDIIYH 320
            |.:.:.:.:.    ..:|.||.:||:.:||.:|.|.||.|:.:.|.|:.|.:.:.:|.|.::|||
plant   245 ALRHLEKSEAACQWGSKLHTFCIGLKGSPDLKAGREVADYLGTRHHELHFTVQDGIDAIEEVIYH 309

  Fly   321 LETYDVTTVRCSLPMLLLARYIKSTGIKMILSGEGADEIFGGYLYFHKAPSYNDFHEELVKRVRQ 385
            :|||||||:|.|.||.|::|.|||.|:||:|||||:||||||||||||||:..:||||..::::.
plant   310 VETYDVTTIRASTPMFLMSRKIKSLGVKMVLSGEGSDEIFGGYLYFHKAPNKKEFHEETCRKIKA 374

  Fly   386 LHLSDCLRANKVAMAKGVELRVPFLDTGFVNHVMQIRPEDKIPGPLNKFGEVQQKRLEKYVLRAA 450
            ||..|||||||...|.|||.||||||..|:|..|.|.||.|:..|       ...|:||:|||.|
plant   375 LHQYDCLRANKSTSAWGVEARVPFLDKEFINVAMSIDPEWKMIRP-------DLGRIEKWVLRNA 432

  Fly   451 FADN---YLPDEVLWRQKEQFSDGVGYDWIDSIRRVATSHVSDQEFSAAALRFPFNTPTTKEAFY 512
            |.|.   |||..:|:||||||||||||.|||.::..|..|||:.....|:..||.|||.||||:|
plant   433 FDDEKNPYLPKHILYRQKEQFSDGVGYSWIDGLKDHANKHVSETMLMNASFVFPDNTPLTKEAYY 497

  Fly   513 YRCIFAEQFPGESAARTVVRWVPRL------------DWGCPEDPSGRAQ-AVH 553
            ||.||.:.|| :||||..|...|.:            .|....||||||. .||
plant   498 YRTIFEKFFP-KSAARATVPGGPSVACSTAKAVEWDAAWSQNLDPSGRAALGVH 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AsnS	NP_996132.1	asnB	1..554	CDD:236513	251/574 (44%)
		AsnB	2..>182	CDD:238364	66/179 (37%)
		Asn_synthase	225..528	CDD:279122	160/309 (52%)
ASN3	NP_196586.1	PLN02549	1..577	CDD:178164	251/574 (44%)
		AsnB	2..192	CDD:238364	73/205 (36%)
		Asn_synthase	210..511	CDD:279122	159/308 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	163	1.000	Domainoid score	I1237
eggNOG	1	0.900	-	-		E1_COG0367
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	452	1.000	Inparanoid score	I384
OMA	1	1.010	-	-		QHG62355
OrthoDB	1	1.010	-	-		D782607at2759
OrthoFinder	1	1.000	-	-		FOG0001900
OrthoInspector	1	1.000	-	-		otm3380
orthoMCL	1	0.900	-	-		OOG6_100710
Panther	1	1.100	-	-	O	PTHR11772
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1254
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.840